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9-CP-Ade Mesylate

Name: 9-CP-Ade Mesylate
Brand: TargetMol
SKU: T23588
Price: 61 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T23588Cas No. 189639-09-6

Alias 9-Cyclopentyladenine monomethanesulfonate, 9CPAde Mesylate, 9 CP Ade Mesylate

9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.

9-CP-Ade Mesylate

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Purity: 99.81%

Catalog No. T23588Alias 9-Cyclopentyladenine monomethanesulfonate, 9CPAde Mesylate, 9 CP Ade MesylateCas No. 189639-09-6

9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$61	In Stock	In Stock
5 mg	$147	In Stock	In Stock
10 mg	$228	-	In Stock
25 mg	$419	-	In Stock
50 mg	$619	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products.If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.81%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	9-CP-Ade Mesylate (9 CP Ade Mesylate) is a cell-permeable, stable and non-competitive inhibitor of adenylate cyclase.
In vitro	9-CP-Ade Mesylate (200 μM; 30 min) inhibits cAMP response element binding protein (CREB) activation and completely blocks neurogenesis in PC12 cells.[1] 9-CP-Ade Mesylate (100 μM; 30 min) attenuates the effects of relaxin on mechanical activity and prevents relaxin-induced hyperpolarization, thereby participating in the regulation of relaxin on ileal smooth muscle activity in female CD1 Swiss mice.[2] 9-CP-Ade Mesylate (100 μM; 6 h) promotes restoration of the keratinocyte permeability barrier by inhibiting cAMP synthesis in male hairless mice.[3]
Synonyms	9-Cyclopentyladenine monomethanesulfonate, 9CPAde Mesylate, 9 CP Ade Mesylate

Chemical Properties

Molecular Weight	299.35
Formula	C₁₁H₁₇N₅O₃S
Cas No.	189639-09-6
Smiles	CS(O)(=O)=O.Nc1ncnc2n(cnc12)C1CCCC1
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 29.94 mg/mL (100.02 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3406 mL	16.7029 mL	33.4057 mL	167.0286 mL
5 mM	0.6681 mL	3.3406 mL	6.6811 mL	33.4057 mL
10 mM	0.3341 mL	1.6703 mL	3.3406 mL	16.7029 mL
20 mM	0.1670 mL	0.8351 mL	1.6703 mL	8.3514 mL
50 mM	0.0668 mL	0.3341 mL	0.6681 mL	3.3406 mL
100 mM	0.0334 mL	0.1670 mL	0.3341 mL	1.6703 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc