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Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $51 | In Stock | |
| 5 mg | $103 | In Stock | |
| 10 mg | $167 | In Stock | |
| 25 mg | $279 | In Stock | |
| 50 mg | $397 | In Stock | |
| 100 mg | $538 | In Stock | |
| 200 mg | $691 | In Stock |
| Description | Cevidoplenib dimesylate hydrochloride is a spleen tyrosine kinase (Syk) inhibitor showing potential immunomodulating and anti-inflammatory properties. |
| In vitro | Cevidoplenib dimesylate hydrochloride(oral) inhibited the activity of SYK and blocked Fc receptor and B-cell receptor (BCR)-mediated signaling in inflammatory cells, including macrophages, mast cells, natural killer cells, B cells, and neutrophils[1]. |
| Molecular Weight | 1957.9 |
| Formula | C90H132Cl5N27O12 |
| Cas No. | 269062-93-3 |
| Smiles | NCCCC[C@@H](C(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H]3N(C([C@H](CC4=CNC5=C4C=CC=C5)NC([C@H](CC6=CNC7=C6C=CC=C7)NC([C@H]8N(C([C@H](CC9=CNC%10=C9C=CC=C%10)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)N)=O)=O)=O)=O)CCC8)=O)=O)=O)CCC3)=O)=O)=O)=O.[H]Cl.[H]Cl.[H]Cl.[H]Cl.[H]Cl |
| Color | White |
| Appearance | Solid |
| Sequence | H-Ile-Leu-Arg-Trp-Pro-Trp-Trp-Pro-Trp-Arg-Arg-Lys-NH2 |
| Sequence Short | ILRWPWWPWRRK |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||
| Solubility Information | DMSO: 19.58 mg/mL (10 mM), Sonication is recommended. | ||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||
DMSO
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