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ELANE Protein, Human, Recombinant (GST)

Catalog No. TMPH-01773
Synonyms: Neutrophil elastase, ELA2, Medullasin, Elastase-2, ELANE, Bone marrow serine protease, Human leukocyte elastase (HLE), PMN elastase

Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro; digests outer membrane protein A (ompA) in E.coli and K.pneumoniae.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
ELANE Protein, Human, Recombinant (GST)
Pack Size Availability Price/USD Quantity
20 μg 20 days $ 198.00
100 μg 20 days $ 389.00
1 mg 20 days $ 1,680.00
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Biological Description
Technical Params
Product Properties
Description Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro; digests outer membrane protein A (ompA) in E.coli and K.pneumoniae.
Species Human
Expression System E. coli
Tag N-terminal GST-tagged
Accession Number P08246
Synonyms Neutrophil elastase, ELA2, Medullasin, Elastase-2, ELANE, Bone marrow serine protease, Human leukocyte elastase (HLE), PMN elastase
Amino Acid IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPHPRDPDPASRTH Note: The complete sequence including tag sequence, target protein sequence and linker sequence could be provided upon request.
Construction 30-267 aa
Protein Purity > 90% as determined by SDS-PAGE.
Molecular Weight 52.6 kDa as predicted
Formulation Tris-based buffer,50% glycerol
Reconstitution A hardcopy of COA with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis. Capable of killing E.coli but not S.aureus in vitro; digests outer membrane protein A (ompA) in E.coli and K.pneumoniae.

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Keywords

ELANE Protein, Human, Recombinant (GST) Neutrophil elastase ELA2 Medullasin Elastase-2 ELANE Bone marrow serine protease Human leukocyte elastase (HLE) PMN elastase recombinant recombinant-proteins proteins protein

 

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