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Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody (Synonyms: p-4EBP1 (Thr46), p-4EBP1 (T46), 4EBP1 (p-Thr46), 4E...)
Catalog No. TMAC-00022 Copy Product Info
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Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody is a Rabbit antibody targeting Phospho-4EBP1 (Thr46). Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody can be used in IHC,WB.
Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody
Copy Product Info🥰Excellent
Catalog No. TMAC-00022
Synonyms p-4EBP1 (Thr46), p-4EBP1 (T46), 4EBP1 (p-Thr46), 4EBP1 (p-T46)
Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody is a Rabbit antibody targeting Phospho-4EBP1 (Thr46). Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody can be used in IHC,WB.
Anti-Phospho-4EBP1
(Thr46) Polyclonal Antibody
(Thr46) Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $216 | 7-10 days | 7-10 days | |
| 100 μL | $317 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody is a Rabbit antibody targeting Phospho-4EBP1 (Thr46). Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody can be used in IHC,WB. |
| Synonyms | p-4EBP1 (Thr46), p-4EBP1 (T46), 4EBP1 (p-Thr46), 4EBP1 (p-T46) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of extracts from Hela cells using 4E-BP1 (Phospho-Thr46) Antibody TMAC-00022 and the same antibody preincubated with blocking peptide. 2. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using 4E-BP1(Phospho-Thr45) Antibody TMAC-00022(left) or the same antibody preincubated with blocking peptide(right).   |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-100 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | 4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of threonine 46 (S-T-T(p)-P-G) derived from Human 4E-BP1 |
| Antigen Species | human |
| Uniprot ID |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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