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Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody

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Catalog No. TMAC-00022
Alias PHAS-I, eukaryotic translation initiation factor 4E binding protein 1, BP-1, BP1, BP 1, 4E-BP1, 4EBP1

Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody is a Rabbit antibody targeting Phospho-4EBP1 (Thr46). Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody can be used in WB,IHC.

Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody

Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody

😃Good
Catalog No. TMAC-00022Alias PHAS-I, eukaryotic translation initiation factor 4E binding protein 1, BP-1, BP1, BP 1, 4E-BP1, 4EBP1
Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody is a Rabbit antibody targeting Phospho-4EBP1 (Thr46). Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3177-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody is a Rabbit antibody targeting Phospho-4EBP1 (Thr46). Anti-Phospho-4EBP1 (Thr46) Polyclonal Antibody can be used in WB,IHC.
AliasPHAS-I, eukaryotic translation initiation factor 4E binding protein 1, BP-1, BP1, BP 1, 4E-BP1, 4EBP1
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-100
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research Background4E-BP1 encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of threonine 46 (S-T-T(p)-P-G) derived from Human 4E-BP1
Antigen Species
human
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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