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Anti-ANAPC11 Antibody (7O517)
😃Good
Catalog No. TMAC-00194
Alias Yeast APC11 homolog, Yeast APC 11 homolog, HSPC214 MGC882, HSPC 214, Hepatocellular carcinoma-associated RING finger protein, Hepatocellular carcinoma associated RING finger protein, Apc11p Cyclosome subunit 11, APC11 APC11_HUMAN, APC11 anaphase promoting complex subunit 11 homolog (yeast), APC11 anaphase promoting complex subunit 11 homolog, Apc 11p, Anaphase-promoting complex subunit 11 Apc 11, Anaphase promoting complex subunit 11 homolog (yeast), Anaphase promoting complex subunit 11 homolog, Anaphase promoting complex subunit 11 (yeast APC11 homolog), Anaphase promoting complex subunit 11, ANAPC 11
Anti-ANAPC11 Antibody (7O517) is a Mouse antibody targeting ANAPC11. Anti-ANAPC11 Antibody (7O517) can be used in WB,FCM.
Anti-ANAPC11 Antibody (7O517)
Anti-ANAPC11 Antibody (7O517)
😃Good
Catalog No. TMAC-00194Alias Yeast APC11 homolog, Yeast APC 11 homolog, HSPC214 MGC882, HSPC 214, Hepatocellular carcinoma-associated RING finger protein, Hepatocellular carcinoma associated RING finger protein, Apc11p Cyclosome subunit 11, APC11 APC11_HUMAN, APC11 anaphase promoting complex subunit 11 homolog (yeast), APC11 anaphase promoting complex subunit 11 homolog, Apc 11p, Anaphase-promoting complex subunit 11 Apc 11, Anaphase promoting complex subunit 11 homolog (yeast), Anaphase promoting complex subunit 11 homolog, Anaphase promoting complex subunit 11 (yeast APC11 homolog), Anaphase promoting complex subunit 11, ANAPC 11
Anti-ANAPC11 Antibody (7O517) is a Mouse antibody targeting ANAPC11. Anti-ANAPC11 Antibody (7O517) can be used in WB,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $426 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-ANAPC11 Antibody (7O517) is a Mouse antibody targeting ANAPC11. Anti-ANAPC11 Antibody (7O517) can be used in WB,FCM. |
| Alias | Yeast APC11 homolog, Yeast APC 11 homolog, HSPC214 MGC882, HSPC 214, Hepatocellular carcinoma-associated RING finger protein, Hepatocellular carcinoma associated RING finger protein, Apc11p Cyclosome subunit 11, APC11 APC11_HUMAN, APC11 anaphase promoting complex subunit 11 homolog (yeast), APC11 anaphase promoting complex subunit 11 homolog, Apc 11p, Anaphase-promoting complex subunit 11 Apc 11, Anaphase promoting complex subunit 11 homolog (yeast), Anaphase promoting complex subunit 11 homolog, Anaphase promoting complex subunit 11 (yeast APC11 homolog), Anaphase promoting complex subunit 11, ANAPC 11 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-1000; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Comprising more than ten subunits, the anaphase-promoting complex (APC) acts in a cell-cycle dependent manner to promote the separation of sister chromatids during the transition between metaphase and anaphase in mitosis. APC, or cyclosome, accomplishes this progression through the ubiquitination of mitotic cyclins and other regulatory proteins that are targeted for destruction during cell division. APC is phosphorylated, and thus activated, by protein kinases Cdk1/cyclin B and polo-like kinase (Plk). APC is under tight control by a number of regulatory factors, including CDC20, CDH1 and MAD2. Specifically, CDC20 and CDH1 directly bind to APC and activates APC's cyclin-ubiquitination activity. In contrast, MAD2 inhibits APC by forming a ternary complex with CDC20 and APC; thus preventing APC activation. APC11 is a RING-H2 finger protein that allows for the synthesis of multiubiquitin chains in the presence of Ubiquitin carrier protein 4 (Ubc4) and ubiquitin conjugating enzyme (E2). In addition, a heterodimeric complex of either Ubc4 or UbcH10 with APC11 and APC2 catalyzes the ubiquitination of human securin and cyclin B1. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 10 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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