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CAY10711 is a substituted diamine that produces rapid bactericidal activity against both Gram-positive and Gram-negative bacteria, including methicillin-resistant S. aureus (MRSA) and stationary-phase bacteria. It displays MIC99 values of 2.9, 11.5, 2.9, and 2.9 μM against S. aureus RN4220, P. aeruginosa PAO1, E. coli ANS1, and MRSA 10082B, respectively. CAY10711 reduces biofilm formation and promotes biofilm dispersal in P. aeruginosa. It is synergistic with kanamycin and has limited adverse effects against mammalian cells or C. elegans development, survival, or reproduction.

| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $246 | 35 days | 35 days | |
| 5 mg | $1,090 | 35 days | 35 days | |
| 10 mg | $1,920 | 35 days | 35 days | |
| 25 mg | $4,230 | 35 days | 35 days |
| Description | CAY10711 is a substituted diamine that produces rapid bactericidal activity against both Gram-positive and Gram-negative bacteria, including methicillin-resistant S. aureus (MRSA) and stationary-phase bacteria. It displays MIC99 values of 2.9, 11.5, 2.9, and 2.9 μM against S. aureus RN4220, P. aeruginosa PAO1, E. coli ANS1, and MRSA 10082B, respectively. CAY10711 reduces biofilm formation and promotes biofilm dispersal in P. aeruginosa. It is synergistic with kanamycin and has limited adverse effects against mammalian cells or C. elegans development, survival, or reproduction. |
| Molecular Weight | 695.04 |
| Formula | C41H54N6S2 |
| Cas No. | 1666171-29-4 |
| Smiles | C(CNC(NCCCNCCCCCNCCCNC(NCC(C1=CC=CC=C1)C2=CC=CC=C2)=S)=S)(C3=CC=CC=C3)C4=CC=CC=C4 |
| Relative Density. | 1.119 g/cm3 (Predicted) |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMF: 20 mg/mL (28.78 mM), Sonication is recommended. Ethanol:PBS (pH7.2)(1:20): 0.04 mg/mL (0.06 mM), Sonication is recommended. Ethanol: 30 mg/mL (43.16 mM), Sonication is recommended. DMSO: 30 mg/mL (43.16 mM), Sonication is recommended. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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