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Anti-PCSK6 Polyclonal Antibody
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Catalog No. TMAB-01344
Alias Subtilisin-like proprotein convertase 4 (SPC4), Subtilisin/kexin-like protease PACE4, Proprotein convertase subtilisin/kexin type 6, PCSK6, Paired basic amino acid cleaving enzyme 4, PACE4
Anti-PCSK6 Polyclonal Antibody is a Rabbit antibody targeting PCSK6. Anti-PCSK6 Polyclonal Antibody can be used in WB,ELISA.
Anti-PCSK6 Polyclonal Antibody
Anti-PCSK6 Polyclonal Antibody
😃Good
Catalog No. TMAB-01344Alias Subtilisin-like proprotein convertase 4 (SPC4), Subtilisin/kexin-like protease PACE4, Proprotein convertase subtilisin/kexin type 6, PCSK6, Paired basic amino acid cleaving enzyme 4, PACE4
Anti-PCSK6 Polyclonal Antibody is a Rabbit antibody targeting PCSK6. Anti-PCSK6 Polyclonal Antibody can be used in WB,ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $221 | 7-10 days | |
| 100 μL | $373 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-PCSK6 Polyclonal Antibody is a Rabbit antibody targeting PCSK6. Anti-PCSK6 Polyclonal Antibody can be used in WB,ELISA. |
| Alias | Subtilisin-like proprotein convertase 4 (SPC4), Subtilisin/kexin-like protease PACE4, Proprotein convertase subtilisin/kexin type 6, PCSK6, Paired basic amino acid cleaving enzyme 4, PACE4 |
| Ig Type | IgG |
| Reactivity | Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep) |
| Verified Activity | Sample: Lane 1: Rat Testis tissue lysates Lane 2: Human 293T cell lysates Lane 3: Human HepG2 cell lysates Lane 4: Human A549 cell lysates Lane 5: Human SH-SY5Y cell lysates Primary: Anti-PACE4 (TMAB-01344) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 91 kDa Observed band size: 135 kDa |
| Application | |
| Recommended Dose | WB: 1:500-2000; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted; Endomembrane system. Retained intracellularly probably through a hydrophobic cluster in their C-terminus and Endoplasmic reticulum. Not secreted, remains probably in zymogen form in endoplasmic reticulum. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Research Background | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues, including neuroendocrine, liver, gut, and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression and left-right patterning. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2014] |
| Immunogen | KLH conjugated synthetic peptide: human PACE4 |
| Antigen Species | Human |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Proprotein Convertases |
| Molecular Weight | Theoretical: 91 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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