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Anti-PCSK6 Polyclonal Antibody

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Catalog No. TMAB-01344
Alias Subtilisin-like proprotein convertase 4 (SPC4), Subtilisin/kexin-like protease PACE4, Proprotein convertase subtilisin/kexin type 6, PCSK6, Paired basic amino acid cleaving enzyme 4, PACE4

Anti-PCSK6 Polyclonal Antibody is a Rabbit antibody targeting PCSK6. Anti-PCSK6 Polyclonal Antibody can be used in WB,ELISA.

Anti-PCSK6 Polyclonal Antibody

Anti-PCSK6 Polyclonal Antibody

😃Good
Catalog No. TMAB-01344Alias Subtilisin-like proprotein convertase 4 (SPC4), Subtilisin/kexin-like protease PACE4, Proprotein convertase subtilisin/kexin type 6, PCSK6, Paired basic amino acid cleaving enzyme 4, PACE4
Anti-PCSK6 Polyclonal Antibody is a Rabbit antibody targeting PCSK6. Anti-PCSK6 Polyclonal Antibody can be used in WB,ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2217-10 days
100 μL$3737-10 days
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Product Introduction

Bioactivity
Description
Anti-PCSK6 Polyclonal Antibody is a Rabbit antibody targeting PCSK6. Anti-PCSK6 Polyclonal Antibody can be used in WB,ELISA.
AliasSubtilisin-like proprotein convertase 4 (SPC4), Subtilisin/kexin-like protease PACE4, Proprotein convertase subtilisin/kexin type 6, PCSK6, Paired basic amino acid cleaving enzyme 4, PACE4
Ig Type
IgG
Reactivity
Human,Rat (predicted:Mouse,Dog,Pig,Cow,Horse,Rabbit,Sheep)
Verified Activity
Sample:
Lane 1: Rat Testis tissue lysates
Lane 2: Human 293T cell lysates
Lane 3: Human HepG2 cell lysates
Lane 4: Human A549 cell lysates
Lane 5: Human SH-SY5Y cell lysates
Primary: Anti-PACE4 (TMAB-01344) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 91 kDa
Observed band size: 135 kDa
Application
WB,ELISA
Recommended Dose
WB: 1:500-2000; ELISA: 1:5000-10000
Antibody Type
Polyclonal
Host SpeciesRabbit
Subcellular LocalizationSecreted; Endomembrane system. Retained intracellularly probably through a hydrophobic cluster in their C-terminus and Endoplasmic reticulum. Not secreted, remains probably in zymogen form in endoplasmic reticulum.
ConstructionHybridoma Polyclonal Antibody
PurificationProtein A purified
AppearanceLiquid
Formulation0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Research BackgroundThis gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the trans-Golgi network where a second autocatalytic event takes place and the catalytic activity is acquired. The encoded protease is constitutively secreted into the extracellular matrix and expressed in many tissues, including neuroendocrine, liver, gut, and brain. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. Some of its substrates include transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression and left-right patterning. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2014]
Antigen Details
Immunogen
KLH conjugated synthetic peptide: human PACE4
Antigen Species
Human
Gene ID
Uniprot ID
Biology Area
Proprotein Convertases
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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