IKZF1 Protein, Human, Recombinant (Avi & His)

Name: IKZF1 Protein, Human, Recombinant (Avi & His)
Brand: TargetMol
SKU: TMPH-01242
Price: 105 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: ZNFN1A1, Lymphoid transcription factor LyF-1, LYF1, IKZF1, Ikaros family zinc finger protein 1, IKAROS, IK1, DNA-binding protein Ikaros) Copy Product Info

Synonyms: ZNFN1A1, Lymphoid transcription factor LyF-1, LYF1, IKZF1, Ikaros family zinc finger protein 1, IKAROS, IK1, DNA-binding protein Ikaros

Catalog No. TMPH-01242 Copy Product Info

IKZF1 Protein, Human, Recombinant (Avi & His) is expressed in E. coli expression system with N-6xHis-Avi tag. The predicted molecular weight is 56.8 kDa and the accession number is Q13422.

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Pack Size	Price	USA Stock	Global Stock
5 µg	$105	-	In Stock
10 µg	$169	-	In Stock
20 µg	$283	20 days	20 days
50 µg	$428	20 days	20 days
100 µg	$590	-	In Stock
200 µg	$913	20 days	20 days
500 µg	$1,620	20 days	20 days
1 mg	$2,530	20 days	20 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:89% (SDS-PAGE)

Appearance:Lyophilized powder

Color:White

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COA User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	IKZF1 Protein, Human, Recombinant (Avi & His) is expressed in E. coli expression system with N-6xHis-Avi tag. The predicted molecular weight is 56.8 kDa and the accession number is Q13422.
Species	Human
Expression System	E. coli
Tag	N-6xHis-Avi
Accession Number	Q13422
Amino Acid	MDADEGQDMSQVSGKESPPVSDTPDEGDEPMPIPEDLSTTSGGQQSSKSDRVVASNVKVETQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCDICGIICIGPNVLMVHKRSHTGERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYACRRRDALTGHLRTHSVIKEETNHSEMAEDLCKIGSERSLVLDRLASNVAKRKSSMPQKFLGDKGLSDTPYDSSASYEKENEMMKSHVMDQAINNAINYLGAESLRPLVQTPPGGSEVVPVISPMYQLHKPLAEGTPRSNHSAQDSAVENLLLLSKAKLVPSEREASPSNSCQDSTDTESNNEEQRSGLIYLTNHIAPHARNGLSLKEEHRAYDLLRAASENSQDALRVVSTSGEQMKVYKCEHCRVLFLDHVMYTIHMGCHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRFHMS
Construction	1-477 aa
Protein Purity	> 85% as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Tris-based buffer, 50% glycerol
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Synonyms	ZNFN1A1, Lymphoid transcription factor LyF-1, LYF1, IKZF1, Ikaros family zinc finger protein 1, IKAROS, IK1, DNA-binding protein Ikaros
Research Background	Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (fikzfterminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs). Function is isoform-specific and is modulated by dominant-negative inactive isoforms.

Chemical Properties

Molecular Weight

56.8 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.