IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His)

Catalog No. TMPY-00470

IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is NP_002181.1&NP_443104.1.

IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His)

Catalog No. TMPY-00470

Pack Size	Price	Availability
100 μg	$397	In Stock
200 μg	$674	7-10 days
500 μg	$2,100	7-10 days

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COA User Guide of Recombinant Proteins

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Product Information

Biological Activity	1.Measured by its binding ability in a functional ELISA._x000D_ 2.Measured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells in the presense of 20 ng/mL TNFα. The ED50 for this effect is 0.8-4 ng/mL.
Description	IL-17A & IL-17F Heterodimer Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is NP_002181.1&NP_443104.1.
Species	Human
Expression System	HEK293 Cells
Tag	C-His
Accession Number	NP_002181.1&NP_443104.1
Synonyms	interleukin 17A,IL-17A,IL-17,IL17,CTLA8
Construction	A DNA sequence encoding the human IL17A (NP_002181.1) (Met1-Ala155) and the mature form of human IL17F (NP_443104.1) (Arg31-Gln163) linked by a polypeptide linker was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Gly 24 & Arg31
Protein Purity	> 95 % as determined by SDS-PAGE.
Molecular Weight	31 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.