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Anti-SFRP4 Polyclonal Antibody
(Synonyms: sFRP-4, secreted frizzled-related protein 4, FRPHE, FRP-4) Copy Product Info
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Synonyms: sFRP-4, secreted frizzled-related protein 4, FRPHE, FRP-4
Catalog No. TMAB-01680 Copy Product Info
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Anti-SFRP4 Polyclonal Antibody is a Rabbit antibody targeting SFRP4. Anti-SFRP4 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-SFRP4 Polyclonal Antibody
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $529 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Antigen Details
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| Description | Anti-SFRP4 Polyclonal Antibody is a Rabbit antibody targeting SFRP4. Anti-SFRP4 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | sFRP-4, secreted frizzled-related protein 4, FRPHE, FRP-4 |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Dog,Pig,Cow,Rabbit) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Secreted. |
| Tissue Specificity | Expressed the ovary. Localized to granulosa cells of periovulatory follicles and corpora lutea. Weakly expressed in adult tissues including kidney, brain and lung. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake. [SUBCELLULAR LOCATION] Secreted. Expressed in mesenchymal cells. Highly expressed in the stroma of proliferative endometrium. Expressed in cardiomyocytes. Belongs to the secreted frizzled-related protein (sFRP) family. |
| Immunogen | KLH conjugated synthetic peptide: human sFRP-4 |
| Antigen Species | Human |
| Gene Name | SFRP4 |
| Gene ID | |
| Protein Name | Secreted frizzled-related protein 4 |
| Uniprot ID | |
| Biology Area | Secreted |
| Function | Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake (By similarity). |
| Molecular Weight | Theoretical: 38 kDa. Actual: 60 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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