Powder: -20°C for 3 years | In solvent: -80°C for 1 year
CYP1B1-IN-5 is a selective and potent cytochrome P450 1B1 (CYP1B1) inhibitor with an IC50 of 4.7 nM.CYP1B1-IN-5 can be used for the study of metabolism-related diseases.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 195.00 | |
5 mg | In stock | $ 483.00 | |
10 mg | In stock | $ 692.00 | |
25 mg | In stock | $ 1,080.00 | |
50 mg | In stock | $ 1,490.00 | |
100 mg | In stock | $ 1,970.00 | |
500 mg | In stock | $ 3,930.00 |
Description | CYP1B1-IN-5 is a selective and potent cytochrome P450 1B1 (CYP1B1) inhibitor with an IC50 of 4.7 nM.CYP1B1-IN-5 can be used for the study of metabolism-related diseases. |
Targets&IC50 | CYP1A1:190.7 nM, CYP1B1:4.7 nM, CYP1A2:585.7 nM |
In vitro | CYP1B1-IN-5 (Compound 6q) binds to the binding pocket of CYP1B1 by forming π-π stacking interactions with residues Phe231, Phe134 and heme.[1] |
Molecular Weight | 349.12 |
Formula | C14H8INO2 |
CAS No. | 176442-56-1 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 5.63 mg/mL (16.11 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
CYP1B1-IN-5 176442-56-1 Metabolism P450 inhibitor inhibit