Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody

😃Good
Catalog No. TMAC-02655

Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RPS6KA5 (Ser360). Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody can be used in IHC-P,ICC/IF,ELISA.

Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody

Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody

😃Good
Catalog No. TMAC-02655
Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RPS6KA5 (Ser360). Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody can be used in IHC-P,ICC/IF,ELISA.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3167-10 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Product Introduction

Bioactivity
Description
Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody is a Rabbit antibody targeting Phospho-RPS6KA5 (Ser360). Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody can be used in IHC-P,ICC/IF,ELISA.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
IHC-P: 1:100-300; ICC/IF: 1:200-1000; ELISA: 1:10000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
AppearanceLiquid
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Research Backgroundcatalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Appears to be activated by multiple phosphorylations on threonine and serine residues. ERK1/2 and MAPK14/p38-alpha may play a role in this process.,function:Serine/threonine kinase required for the mitogen or stress-induced phosphorylation of the transcription factors CREB (cAMP response element-binding protein) and ATF1 (activating transcription factor-1). Essential role in the control of RELA transcriptional activity in response to TNF. Directly represses transcription via phosphorylation of 'Ser-1' of histone H2A. Phosphorylates 'Ser-10' of histone H3 in response to mitogenics, stress stimuli and epidemal growth-factor (EGF), which results in the transcriptional activation of several immediate early genes, including proto-oncogenes c-fos/FOS and c-jun/JUN. May also phosphorylate 'Ser-28' of histone H3. Mediates the mitogen- and stress-induced phosphorylation of high mobility group protein 14 (HMG-14).,miscellaneous:Enzyme activity requires the presence of both kinase domains.,PTM:Ser-376 and Thr-581 phosphorylation is required for kinase activity. Ser-376 and Ser-212 are autophosphorylated by the C-terminal kinase domain, and their phosphorylation is essential for the catalytic activity of the N-terminal kinase domain.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 2 protein kinase domains.,subcellular location:Predominantly nuclear. Partially cytoplasmic.,subunit:Forms a complex with either ERK1 or ERK2 in quiescent cells which transiently dissociates following mitogenic stimulation. Also associates with MAPK14/p38-alpha. Activated RPS6KA5 associates with and phosphorylates the NF-kappa-B p65 subunit RELA.,tissue specificity:Widely expressed with high levels in heart, brain and placenta. Less abundant in lung, kidney and liver.,
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
A synthesized phosphopeptide: human MSK1 around the phosphorylation site of Ser360. AA range:331-380
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 89 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody | purchase Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody | Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody cost | order Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody | Anti-Phospho-RPS6KA5 (Ser360) Polyclonal Antibody molecular weight