Shopping Cart
Remove All
Your shopping cart is currently empty
Iso-OMPA
😃Good
Catalog No. T86746Cas No. 513-00-8
Alias Tetraisopropyl pyrophosphoramide
Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective, covalent, and irreversible butylcholinesterase (BuChE) inhibitor for studying BuChE-related diseases.
Iso-OMPA
😃Good
Purity: 98.66%
Catalog No. T86746Alias Tetraisopropyl pyrophosphoramideCas No. 513-00-8
Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective, covalent, and irreversible butylcholinesterase (BuChE) inhibitor for studying BuChE-related diseases.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $93 | - | In Stock | |
| 5 mg | $228 | - | In Stock | |
| 10 mg | $372 | - | In Stock | |
| 25 mg | $745 | - | In Stock | |
| 50 mg | $1,180 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $253 | - | In Stock |
Add to Cart
Add to Quotation
In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Batch Information
Select Batch
Purity:98.66%
Contact us for more batch information
Product Introduction
Bioactivity
Chemical Properties
| Description | Iso-OMPA (Tetraisopropyl pyrophosphoramide) is a selective, covalent, and irreversible butylcholinesterase (BuChE) inhibitor for studying BuChE-related diseases. |
| In vitro | Iso-OMPA exhibited IC₅₀ values of 694.7 μM (brain), 10.56 μM (liver), and 9.84 μM (muscle) for propionylthiocholine iodide (PSCh) in the brain, liver, and muscle tissues of the brown shrimp Penaeus aztecus, respectively [1]. For butyrylthiocholine iodide (BSCh), Iso-OMPA showed IC₅₀ values of 12.49 μM (liver) and 11.42 μM (muscle) in the liver and muscle tissues of P. aztecus, with corresponding Ki values of 0.2019 μM (liver) and 0.6612 μM (muscle) [1]. Iso-OMPA (100 μM, treated for 30 minutes) increased the sensitivity of isolated bronchial preparations from Homo sapiens to acetylcholine [2]. |
| In vivo | Iso-OMPA (0.6 and 1.9 mg/kg, subcutaneous injection, single dose) only slightly inhibited rat plasma cholinesterase (CarbE) activity at the low dose, while significantly inhibiting its activity at the high dose; however, no obvious inhibitory effect was observed on mouse plasma CarbE activity [3]. |
| Synonyms | Tetraisopropyl pyrophosphoramide |
| Molecular Weight | 342.36 |
| Formula | C12H32N4O3P2 |
| Cas No. | 513-00-8 |
| Smiles | O=P(OP(=O)(NC(C)C)NC(C)C)(NC(C)C)NC(C)C |
| Color | White |
| Appearance | Solid |
Storage & Solubility Information
| Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 80 mg/mL (233.67 mM), Sonication is recommended. H2O: 8 mg/mL (23.37 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
| In Vivo Formulation | 10% DMSO+40% PEG300+5% Tween-80+45% Saline: 3.3 mg/mL (9.64 mM), Sonication is recommeded. Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions. | ||||||||||||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||||||||||||
H2O/DMSO
DMSO
| |||||||||||||||||||||||||||||||||||||||||
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Iso-OMPA | purchase Iso-OMPA | Iso-OMPA cost | order Iso-OMPA | Iso-OMPA chemical structure | Iso-OMPA in vivo | Iso-OMPA in vitro | Iso-OMPA formula | Iso-OMPA molecular weight
Generate Quote
Catalog No.: Cas No.:
Add
| Size | Quantity | Unit Price | Amount | Operation |
|---|
Generate Quote
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2026 TargetMol Chemicals Inc. All Rights Reserved.