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Vilaprisan

🥰Excellent
Catalog No. T35054Cas No. 1262108-14-4
Alias BAY10-02670, BAY-10-02670, BAY-1002670, BAY1002670, BAY 10-02670, BAY 1002670

Vilaprisan (BAY 1002670) is a novel orally available and selective progesterone receptor modulator (SPRM) with antiproliferative activity against uterine fibroids (UF) and can be used for the study of uterine fibroids.

Vilaprisan

Vilaprisan

🥰Excellent
Purity: 99.83%
Catalog No. T35054Alias BAY10-02670, BAY-10-02670, BAY-1002670, BAY1002670, BAY 10-02670, BAY 1002670Cas No. 1262108-14-4
Vilaprisan (BAY 1002670) is a novel orally available and selective progesterone receptor modulator (SPRM) with antiproliferative activity against uterine fibroids (UF) and can be used for the study of uterine fibroids.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$195In StockIn Stock
5 mg$465In StockIn Stock
10 mg$679In StockIn Stock
25 mg$1,070In StockIn Stock
50 mg$1,430In StockIn Stock
100 mg$1,930In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.
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Batch Information

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Purity:99.83%
ee:97.88%
Appearance:Solid
Color:White
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Product Introduction

Bioactivity
Description
Vilaprisan (BAY 1002670) is a novel orally available and selective progesterone receptor modulator (SPRM) with antiproliferative activity against uterine fibroids (UF) and can be used for the study of uterine fibroids.
In vitro
Vilaprisan shows an IC50 of 0.09 nM in the PR transactivation assay[2].
SynonymsBAY10-02670, BAY-10-02670, BAY-1002670, BAY1002670, BAY 10-02670, BAY 1002670
Chemical Properties
Molecular Weight544.57
FormulaC27H29F5O4S
Cas No.1262108-14-4
SmilesC[C@@]12[C@]([C@]3(C([C@H](C1)C4=CC=C(S(C)(=O)=O)C=C4)=C5C(CC3)=CC(=O)CC5)[H])(CC[C@]2(C(C(F)(F)F)(F)F)O)[H]
Relative Density.1.41 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 7.86 mg/mL (14.43 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8363 mL9.1816 mL18.3631 mL91.8156 mL
5 mM0.3673 mL1.8363 mL3.6726 mL18.3631 mL
10 mM0.1836 mL0.9182 mL1.8363 mL9.1816 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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