Claudin-18 Protein-VLP, Mouse, Recombinant (His)

Catalog No. TMPH-02586

Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-18 Protein-VLP, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis (This tag can be tested only under denaturing conditions) tag. The predicted molecular weight is 29.1 kDa and the accession number is P56857.

Claudin-18 Protein-VLP, Mouse, Recombinant (His)

Catalog No. TMPH-02586

Pack Size	Price	Availability
5 μg	$275	20 days
10 μg	$459	20 days
20 μg	$776	20 days
50 μg	$1,270	20 days
100 μg	$1,870	20 days
200 μg	$3,150	20 days
500 μg	$6,280	20 days

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Product Information

Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized Mouse Cldn18 at 5 μg/mL can bind Anti-CLDN18.2 recombinant antibody, the EC 50 is 6.115-11.01 ng/mL.
Description	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-18 Protein-VLP, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis (This tag can be tested only under denaturing conditions) tag. The predicted molecular weight is 29.1 kDa and the accession number is P56857.
Species	Mouse
Expression System	HEK293 Cells
Tag	N-6xHis (This tag can be tested only under denaturing conditions)
Accession Number	P56857
Synonyms	Cldn18,Claudin-18
Amino Acid	MSVTACQGLGFVVSLIGFAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECRGYFTLLGLPAMLQAVRALMIVGIVLGVIGILVSIFALKCIRIGSMDDSAKAKMTLTSGILFIISGICAIIGVSVFANMLVTNFWMSTANMYSGMGGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLTPDDSNFKAVSYHASGQNVAYRPGGFKASTGFGSNTRNKKIYDGGARTEDDEQSHPTKYDYV
Construction	1-264 aa
Molecular Weight	29.1 kDa (predicted)
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 6% Trehalose, pH 7.4
Reconstitution	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.