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Claudin-18 Protein-VLP, Mouse, Recombinant (His)

Claudin-18 Protein-VLP, Mouse, Recombinant (His)
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Claudin-18 Protein-VLP, Mouse, Recombinant (His)

Catalog No. TMPH-02586
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-18 Protein-VLP, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis (This tag can be tested only under denaturing conditions) tag. The predicted molecular weight is 29.1 kDa and the accession number is P56857.
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Pack SizePriceAvailabilityQuantity
20 μg$53020 days
100 μg$1,06020 days
1 mg$5,63020 days
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Biological Description

Biological Information
Measured by its binding ability in a functional ELISA. Immobilized Mouse Cldn18 at 5 μg/mL can bind Anti-CLDN18.2 recombinant antibody, the EC 50 is 6.115-11.01 ng/mL.
Description
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-18 Protein-VLP, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis (This tag can be tested only under denaturing conditions) tag. The predicted molecular weight is 29.1 kDa and the accession number is P56857.
Species
Mouse
Expression System
HEK293 Cells
TagN-6xHis (This tag can be tested only under denaturing conditions)
Accession NumberP56857
Synonyms
Claudin 18,CLDN18
Amino Acid
MSVTACQGLGFVVSLIGFAGIIAATCMDQWSTQDLYNNPVTAVFNYQGLWRSCVRESSGFTECRGYFTLLGLPAMLQAVRALMIVGIVLGVIGILVSIFALKCIRIGSMDDSAKAKMTLTSGILFIISGICAIIGVSVFANMLVTNFWMSTANMYSGMGGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLTPDDSNFKAVSYHASGQNVAYRPGGFKASTGFGSNTRNKKIYDGGARTEDDEQSHPTKYDYV
Construction
1-264 aa
Molecular Weight29.1 kDa (predicted)
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 6% Trehalose, pH 7.4
Reconstitution
Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
Research Background
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

Dose Conversion

You can also refer to dose conversion for different animals. More

Tech Support

Please read the User Guide of Recombinant Proteins for more specific information.