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Anti-ALAS2 Antibody (2M567) (Synonyms: XLSA, XLEPP, XLDPP, SIDBA1, RP23-338A17.1, OTTMUSP00000020679, OTTH...)

Catalog No. TMAC-00131 Copy Product Info
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Anti-ALAS2 Antibody (2M567) is a Mouse antibody targeting ALAS2. Anti-ALAS2 Antibody (2M567) can be used in IF,IHC-P,IP,WB.

Anti-ALAS2 Antibody (2M567)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00131
Synonyms XLSA, XLEPP, XLDPP, SIDBA1, RP23-338A17.1, OTTMUSP00000020679, OTTHUMP00000023389, OTTHUMP00000023388, mitochondrial, HEM0_HUMAN, FLJ93603, erythroid-specific, Erythroid specific ALAS, Delta-aminolevulinate synthase 2, Delta-ALA synthase 2, Delta aminolevulinate synthase 2, Delta aminolevulinate synthase, Delta ALA synthetase, Delta ALA synthase 2, ASB, ANH1, Aminolevulinic acid synthase 2, erythroid, Aminolevulinate delta synthase 2, ALAS-E, ALASE, Alas2, ALAS, erythroid, ALAS E, Alas 2, ALAS, 5-aminolevulinic acid synthase 2, 5-aminolevulinate synthase, 5 aminolevulinic acid synthase 2, 5 aminolevulinic acid synthase, 5 aminolevulinate synthase erythroid specific mitochondrial, 5 aminolevulinate synthase 5 aminolevulinate synthase 2, 5 aminolevulinate synthase 2, 5 @aminolevulinate synthase erythroid specific

Anti-ALAS2 Antibody (2M567) is a Mouse antibody targeting ALAS2. Anti-ALAS2 Antibody (2M567) can be used in IF,IHC-P,IP,WB.

Anti-ALAS2 Antibody
(2M567)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4267-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-ALAS2 Antibody (2M567) is a Mouse antibody targeting ALAS2. Anti-ALAS2 Antibody (2M567) can be used in IF,IHC-P,IP,WB.
SynonymsXLSA, XLEPP, XLDPP, SIDBA1, RP23-338A17.1, OTTMUSP00000020679, OTTHUMP00000023389, OTTHUMP00000023388, mitochondrial, HEM0_HUMAN, FLJ93603, erythroid-specific, Erythroid specific ALAS, Delta-aminolevulinate synthase 2, Delta-ALA synthase 2, Delta aminolevulinate synthase 2, Delta aminolevulinate synthase, Delta ALA synthetase, Delta ALA synthase 2, ASB, ANH1, Aminolevulinic acid synthase 2, erythroid, Aminolevulinate delta synthase 2, ALAS-E, ALASE, Alas2, ALAS, erythroid, ALAS E, Alas 2, ALAS, 5-aminolevulinic acid synthase 2, 5-aminolevulinate synthase, 5 aminolevulinic acid synthase 2, 5 aminolevulinic acid synthase, 5 aminolevulinate synthase erythroid specific mitochondrial, 5 aminolevulinate synthase 5 aminolevulinate synthase 2, 5 aminolevulinate synthase 2, 5 @aminolevulinate synthase erythroid specific
Clone
2M567
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of ALAS-E expression in non-transfected (A)and human ALAS-E transfected (B) 293T whole cell lysates.
2. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cervix tissue showing cytoplasmic staining of squamous epithelial cells.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:100-1000; IHC-P: 1:50-500; IP: 1-2 μg per 100-500 μg of total protein (1 ml of cell lysate)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research Background5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells. Succinyl CoA associates with ALAS-E in protein conformation change and translocation of ALAS-E into the mitochondria and does not interact with ALAS-H. The ALAS-E 5'-flanking region contains binding sites for nuclear activators such as GATA-1, NF-E2 and EKLF. Since the ALAS gene maps to the X chromosome, mutation of the gene leads to the pyridoxine-refractory X-linked sideroblastic anemia.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Peptide
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 60 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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