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Anti-VSIG4 Antibody-HRP (4U482)
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Catalog No. TMAY-02259H
Alias Z39IG, V-set and immunoglobulin domain containing 4, CRIg
Anti-VSIG4 Antibody-HRP (4U482) is a HRP-conjugated Rabbit antibody targeting VSIG4. Anti-VSIG4 Antibody-HRP (4U482) can be used in ELISA.
Anti-VSIG4 Antibody-HRP (4U482)
Anti-VSIG4 Antibody-HRP (4U482)
😃Good
Catalog No. TMAY-02259HAlias Z39IG, V-set and immunoglobulin domain containing 4, CRIg
Anti-VSIG4 Antibody-HRP (4U482) is a HRP-conjugated Rabbit antibody targeting VSIG4. Anti-VSIG4 Antibody-HRP (4U482) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μg | $446 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | Z39IG, V-set and immunoglobulin domain containing 4, CRIg |
| Ig Type | Rabbit IgG |
| Clone | 4U482 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 0.1-1 μg/ml |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human VSIG4 (rh VSIG4; TMPY-01907; Q9Y279-1; Met 1-Pro 283), and conjugated with horseradish-peroxidase (HRP). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | VSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces. No VSIG4 expression appears to be present in T and B cells. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. Mouse VSIG4 is synthesized as a 28 amino acid precursor that contains a signal sequence, a V-type I g domain (aa 36-115), one potential N-linked glycosylation site, and a single transmembrane domain. The V-type I g domain of mouse VSIG4 shares 86% and 8% aa sequence identity with the V-type I g domains of rat and human VSIG4, respectively. |
| Conjucates | HRP |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Protein: Human VSIG4 protein (TMPY-01907) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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