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Anti-VSIG4 Antibody-HRP (4U482) (Synonyms: Z39IG, V-set and immunoglobulin domain containing 4, CRIg)

Catalog No. TMAY-02259H Copy Product Info
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Anti-VSIG4 Antibody-HRP (4U482) is a HRP-conjugated Rabbit antibody targeting VSIG4. Anti-VSIG4 Antibody-HRP (4U482) can be used in ELISA.

Anti-VSIG4 Antibody-HRP (4U482)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02259H
Synonyms Z39IG, V-set and immunoglobulin domain containing 4, CRIg

Anti-VSIG4 Antibody-HRP (4U482) is a HRP-conjugated Rabbit antibody targeting VSIG4. Anti-VSIG4 Antibody-HRP (4U482) can be used in ELISA.

Anti-VSIG4 Antibody-HRP
(4U482)
Pack SizePriceUSA StockGlobal StockQuantity
100 μg$4467-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-VSIG4 Antibody-HRP (4U482) is a HRP-conjugated Rabbit antibody targeting VSIG4. Anti-VSIG4 Antibody-HRP (4U482) can be used in ELISA.
SynonymsZ39IG, V-set and immunoglobulin domain containing 4, CRIg
Ig Type
Rabbit IgG
Clone
4U482
Reactivity
Human
Specificity
Human VSIG4
Application
Recommended Dose
ELISA: 0.1-1 μg/ml
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human VSIG4 (rh VSIG4; TMPY-01907; Q9Y279-1; Met 1-Pro 283), and conjugated with horseradish-peroxidase (HRP).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundVSIG4 (V-set and immunoglobulin domain containing 4), also known as complement receptor of the immunoglobulin superfamily (CRIg) and Z39Ig, is a type I transmembrane glycoprotein. It is a B7 family-related protein and an Ig superfamily member. In contrast to the B7 family members which contain two IgG domains, VSIG4 contains one complete V-type I g domain and a truncated C-type I g domain. VSIG4 is exclusively expressed on tissue resident macrophages and binds to multimers of C3b and iC3b that are covalently attached to particle surfaces. No VSIG4 expression appears to be present in T and B cells. VSIG4 functions as a negative regulator of T cell activation, and may be involved in the maintenance of peripheral T cell tolerance, and is also identified as a potent suppressor of established inflammation. Mouse VSIG4 is synthesized as a 28 amino acid precursor that contains a signal sequence, a V-type I g domain (aa 36-115), one potential N-linked glycosylation site, and a single transmembrane domain. The V-type I g domain of mouse VSIG4 shares 86% and 8% aa sequence identity with the V-type I g domains of rat and human VSIG4, respectively.
Related Conjugates and Formulations
Conjucates
HRP
Others Formats
Unconjugated
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Protein: Human VSIG4 protein (TMPY-01907)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
TransportShipping with blue ice.

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