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CD72 Protein, Human, Recombinant (Trx & His)

(Synonyms: Lyb-2, CD72, B-Cell Differentiation Antigen CD72) Copy Product Info

Synonyms: Lyb-2, CD72, B-Cell Differentiation Antigen CD72

Catalog No. TMPJ-00898 Copy Product Info
B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.
CD72 Protein, Human, Recombinant (Trx & His)
Pack SizePriceUSA StockGlobal StockQuantity
5 μg$1127-10 days7-10 days
10 μg$1837-10 days7-10 days
20 μg$2927-10 days7-10 days
50 μg$5457-10 days7-10 days
100 μg$8137-10 days7-10 days
200 μg$1,1907-10 days7-10 days
500 μg$2,0707-10 days7-10 days
1 mg$2,9707-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description
B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.
Species
Human
Expression System
E. coli
TagN-Trx-6xHis
Accession NumberP21854
Amino AcidArg117-Cys226
ConstructionArg117-Cys226
Protein Purity
Greater than 90% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & StorageLyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
SynonymsLyb-2, CD72, B-Cell Differentiation Antigen CD72
Research Background
Chemical Properties
Molecular Weight26-35 KDa (reducing condition)
Storage & Solubility Information
StorageLyophilized powder: -20~-80°C for 1 year | Solution: -80°C for 6 months

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: CD72 Protein, Human, Recombinant (Trx & His) chemical structure | CD72 Protein, Human, Recombinant (Trx & His) molecular weight