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Anti-Phospho-EGF Receptor (Tyr845) Antibody (8P639) (Alias: PIG61, Phospho-EGF Receptor (Y845), p-EGF Recep...)
Catalog No. TMAY-01616 Copy Product Info
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Anti-Phospho-EGF Receptor (Tyr845) Antibody (8P639) is a Rabbit antibody targeting Phospho-EGF Receptor (Tyr845). Anti-Phospho-EGF Receptor (Tyr845) Antibody (8P639) can be used in WB.
Anti-Phospho-EGF Receptor (Tyr845) Antibody (8P639)
Copy Product Info🥰Excellent
Catalog No. TMAY-01616
Alias PIG61, Phospho-EGF Receptor (Y845), p-EGF Receptor (Y845), p-EGF Receptor (Tyr845), NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB, EGF Receptor (p-Y845), EGF Receptor (p-Tyr845)
Anti-Phospho-EGF Receptor (Tyr845) Antibody (8P639) is a Rabbit antibody targeting Phospho-EGF Receptor (Tyr845). Anti-Phospho-EGF Receptor (Tyr845) Antibody (8P639) can be used in WB.
Anti-Phospho-EGF Receptor
(Tyr845) Antibody
(8P639)
(Tyr845) Antibody
(8P639)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 μL | $81 | 7-10 days | 7-10 days | |
| 100 μL | $233 | 7-10 days | 7-10 days |
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-Phospho-EGF Receptor (Tyr845) Antibody (8P639) is a Rabbit antibody targeting Phospho-EGF Receptor (Tyr845). Anti-Phospho-EGF Receptor (Tyr845) Antibody (8P639) can be used in WB. |
| Synonyms | PIG61, Phospho-EGF Receptor (Y845), p-EGF Receptor (Y845), p-EGF Receptor (Tyr845), NISBD2, mENA, HER-1, HER1, ERRP, ERBB-1, ERBB1, ERBB, EGF Receptor (p-Y845), EGF Receptor (p-Tyr845) |
| Ig Type | Rabbit IgG |
| Clone | 8P639 |
| Reactivity | Human;
Species predicted to react based on 100% sequence homology: Mouse, rat |
| Specificity | Human
Species predicted to react based on 100% sequence homology: Mouse, rat |
| Verified Activity | 1. Western blot analysis of extracts from serum-starved Hela, untreated (-) or treated with EGF (10 ng/mL, 10min) using Phospho-EGF Receptor (Tyr845) rabbit monoclonal Antibody at 1:1000 dilution (upper), Anti-EGFR Antibody at 1:1000 dilution (lower).
2. Western blot analysis of extracts from serum-starved Hela, untreated (line A); treated with EGF (100ng/mL, 10min; +) (line B); treated with EGF and λ-phosphatase (line C) using Phospho-EGF Receptor (Tyr845) rabbit monoclonal Antibody at 1:1000 dilution. (Validation Experiment) 3. Western blot analysis of extracts from serum-starved Hela, untreated (line A); treated with EGF (100ng/mL, 10min), without peptide (line B) or antigen-specific phosphopeptide (line C) or antigen-specific peptide (line D) using Phospho-EGF Receptor (Tyr845) rabbit monoclonal Antibody at 1:1000 dilution. (Validation Experiment) |
| Application | |
| Recommended Dose | WB: 1:1000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with a synthetic phosphopeptide corresponding to residues around Tyr845 of the Human Phospho-EGF Receptor. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| Research Background | As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: residues around Tyr845 of the Human Phospho-EGF Receptor |
| Antigen Species | Human |
| Biology Area | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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