CSNK2A2 Protein, Human, Recombinant (His & GST)

Name: CSNK2A2 Protein, Human, Recombinant (His & GST)
Brand: TargetMol
SKU: TMPY-04393
Price: 93 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: CSNK2A1, CK2A2, casein kinase 2, α prime polypeptide, casein kinase 2, alpha prime polypeptide) Copy Product Info

Synonyms: CSNK2A1, CK2A2, casein kinase 2, α prime polypeptide, casein kinase 2, alpha prime polypeptide

Catalog No. TMPY-04393 Copy Product Info

CSNK2A2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69 kDa and the accession number is P19784.

Pack Size	Price	USA Stock	Global Stock
5 µg	$93	-	In Stock
10 µg	$152	-	In Stock
20 µg	$248	7-10 days	7-10 days
50 µg	$577	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Purity:> 92 % as determined by SDS-PAGE

Appearance:Solution

Color:Transparent

Resource Download

COA User Guide of Recombinant Proteins

Product Information

Bioactivity

Bioactivity	The specific activity was determined to be 30 nmol/min/mg using casein as substrate.
Description	CSNK2A2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 69 kDa and the accession number is P19784.
Species	Human
Expression System	Baculovirus Insect Cells
Tag	His, GST
Accession Number	P19784
Construction	A DNA sequence encoding the human CSNK2A2 (NP_001887.1) (Met 1-Arg 350) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus. Predicted N terminal: Met
Protein Purity	> 92 % as determined by SDS-PAGE
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Supplied as sterile 50 mM Tris, 500 mM NaCl, 0.5 mM PMSF, 0.5 mM TCEP, 10% gly, pH 8.5.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Synonyms	CSNK2A1, CK2A2, casein kinase 2, α prime polypeptide, casein kinase 2, alpha prime polypeptide
Research Background	Casein kinase II subunit alpha', also known as CSNK2A2 and CK2A2, is a member of the protein kinase superfamily, Ser/Thr protein kinase family and CK2 subfamily. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. CSNK2A2 is a tetramer composed of an alpha chain, an alpha' and two beta chains. It is also component of a CK2-SPT16-SSRP1 complex composed of SSRP1, SUPT16H, CSNK2A1, CSNK2A2 and CSNK2B, the complex associating following UV irradiation. Protein kinase casein kinase II (Ck2) is a cyclic-AMP and calcium-independent serine-threonine kinase that is composed of two catalytic subunits (alpha and alpha') and two regulatory beta-subunits. Ck2 is not a casein kinase in vivo, but over 1 substrates are known. The highly conserved amino acid sequences of its subunits and their broad expression suggest that Ck2 may have a fundamental role in cell function. Ck2 has been implicated in DNA replication, regulation of basal and inducible transcription, translation and control of metabolism. The Ck2alpha and Ck2alpha' isoforms (products of the genes Csnk2a1 and Csnk2a2, respectively) are highly homologous, the reason for their redundancy and evolutionary conservation is unknown. CSNK2A2 may be a candidate gene for these inherited syndromes.

Chemical Properties

Molecular Weight

69 kDa (predicted); 60 kDa (reducing conditions)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	It is recommended to store the product under sterile conditions at -20°C to -80°C. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.