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Anti-HAMP Antibody (6Z883)

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Catalog No. TMAC-01799
Alias Putative liver tumor regressor, Liver-expressed antimicrobial peptide 1, LEAP1, HEPC

Anti-HAMP Antibody (6Z883) is a Rabbit antibody targeting HAMP. Anti-HAMP Antibody (6Z883) can be used in WB,IHC.

Anti-HAMP Antibody (6Z883)

Anti-HAMP Antibody (6Z883)

😃Good
Catalog No. TMAC-01799Alias Putative liver tumor regressor, Liver-expressed antimicrobial peptide 1, LEAP1, HEPC
Anti-HAMP Antibody (6Z883) is a Rabbit antibody targeting HAMP. Anti-HAMP Antibody (6Z883) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-HAMP Antibody (6Z883) is a Rabbit antibody targeting HAMP. Anti-HAMP Antibody (6Z883) can be used in WB,IHC.
SynonymsPutative liver tumor regressor, Liver-expressed antimicrobial peptide 1, LEAP1, HEPC
Ig Type
IgG
Clone
6Z883
Reactivity
Human,Rat
Verified Activity
1. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti- Hepcidin antibody. Counter stained with hematoxylin.
2. Immunohistochemical analysis of paraffin-embedded rat heart tissue using anti- Hepcidin antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti- Hepcidin antibody. Counter stained with hematoxylin.
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundHepcidin, also known as HAMP, HEPC, LEAP1 or HFE2B, is an 84 amino acid secreted protein that regulates iron-related signaling events. Highly expressed in liver with lower expression in heart, brain, lung, prostate and thyroid, hepcidin is thought to maintain iron homeostasis and, in conjunction with the HFE protein (a protein that is defective in hereditary hemochromatosis), may mediate both iron storage in macrophages and intestinal iron absorption. Additionally, hepcidin has strong antimicrobial activity against gram-positive and gram-negative bacteria, as well as certain yeast strains, suggesting that hepcidin may play a crucial role in staving off bacterial infections. Defects in the gene encoding hepcidin are the cause of hemochromatosis type 2B (also known as juvenile hemochromatosis), an early-onset autosomal recessive disorder that results in severe iron overload and is characterized by hepatic fibrosis, hypogonadotrophic hypogonadism and cardiomyopathy.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 3 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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