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PFKP Protein, Human, Recombinant (His & GST)

Catalog No. TMPY-05160
Synonyms: PFK-P, PFKF, ATP-PFK, phosphofructokinase, platelet, PFK-C

PFKP plays a critical role in cell proliferation in breast cancer cells. PFKP is necessary for starvation-mediated autophagy, glycolysis, and EMT, thereby promoting the malignant progression of OSCC. The Snail-PFKP axis plays an important role in cancer cell survival via regulation of glucose flux between glycolysis and PPP.

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PFKP Protein, Human, Recombinant (His & GST)
Pack Size Availability Price/USD Quantity
50 μg 5 days $ 600.00
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Biological Description
Technical Params
Product Properties
Description PFKP plays a critical role in cell proliferation in breast cancer cells. PFKP is necessary for starvation-mediated autophagy, glycolysis, and EMT, thereby promoting the malignant progression of OSCC. The Snail-PFKP axis plays an important role in cancer cell survival via regulation of glucose flux between glycolysis and PPP.
Species Human
Expression System Baculovirus-Insect Cells
Tag His,GST
Accession Number Q01813-1
Synonyms PFK-P, PFKF, ATP-PFK, phosphofructokinase, platelet, PFK-C
Construction A DNA sequence encoding the human PFKP (NP_002618.1) (Met1-Val784) was expressed with a C-terminal polyhistidine-tagged GST tag at the N-terminus (his-GST).
Protein Purity > 85 % as determined by SDS-PAGE
Molecular Weight Approxiamtely 113.4 kDa
Endotoxin < 1.0 EU per μg protein as determined by the LAL method.
Formulation Lyophilized from sterile 20 mM Tris, 300 mM NaCl, 10% glycerol, pH 8.0,0. 5 mM TCEP. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Research Background PFKP plays a critical role in cell proliferation in breast cancer cells. PFKP is necessary for starvation-mediated autophagy, glycolysis, and EMT, thereby promoting the malignant progression of OSCC. The Snail-PFKP axis plays an important role in cancer cell survival via regulation of glucose flux between glycolysis and PPP.

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Keywords

PFKP Protein, Human, Recombinant (His & GST) PFK-P PFKF ATP-PFK phosphofructokinase, platelet PFK-C recombinant recombinant-proteins proteins protein

 

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