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Anti-EXT1 Polyclonal Antibody is a Rabbit antibody targeting EXT1. Anti-EXT1 Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $528 | 7-10 days | 7-10 days |
| Description | Anti-EXT1 Polyclonal Antibody is a Rabbit antibody targeting EXT1. Anti-EXT1 Polyclonal Antibody can be used in ELISA,ICC/IF,IF,IHC-Fr,IHC-P. |
| Synonyms | TTV, TRPS2, Putative tumor suppressor protein EXT1, N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase, Multiple exostoses protein 1 homolog, Multiple exostoses protein 1, LGS, LGCR, Langer-Giedion syndrome chromosome region, Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, EXT1, Exostosin 1, exostoses(multiple) 1, 4-alpha-N-acetylglucosaminyltransferase |
| Ig Type | IgG |
| Reactivity | (predicted:Human,Mouse,Rat,Chicken,Cow,Horse,Rabbit,Baboon,Chinese Hamster, Orangutan) |
| Application | |
| Recommended Dose | IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:100-500; IF: 1:100-500; ELISA: 1:5000-10000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Endoplasmic reticulum membrane. Golgi apparatus membrane. The EXT1/EXT2 complex is localized in the Golgi apparatus. |
| Tissue Specificity | Ubiquitous. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | This gene encodes an endoplasmic reticulum-resident type II transmembrane glycosyltransferase involved in the chain elongation step of heparan sulfate biosynthesis. Mutations in this gene cause the type I form of multiple exostoses. [provided by RefSeq, Jul 2008] |
| Immunogen | KLH conjugated synthetic peptide: human EXT1 |
| Antigen Species | Human |
| Gene Name | EXT1 |
| Gene ID | |
| Protein Name | Exostosin-1 |
| Uniprot ID | |
| Biology Area | HSPGs |
| Function | Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor. |
| Molecular Weight | Theoretical: 86 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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