Lp-PLA2/PLA2G7 Protein, Mouse, Recombinant (His)

Name: Lp-PLA2/PLA2G7 Protein, Mouse, Recombinant (His)
Brand: TargetMol
SKU: TMPY-04692
Rating: 4.5 (1 reviews)

(Synonyms: R75400, phospholipase A2 group VII) Copy Product Info

Synonyms: R75400, phospholipase A2 group VII

Catalog No. TMPY-04692 Copy Product Info

Lp-PLA2/PLA2G7 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.3 kDa and the accession number is Q60963.

Pack Size	Price	EUR Stock	Global Stock
5 µg	115 €	7-10 days	7-10 days
10 µg	188 €	7-10 days	7-10 days
20 µg	316 €	7-10 days	7-10 days
50 µg	630 €	-	In Stock

For In stock only · Estimated delivery: EUR Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Batch Information

Select Batch

Purity:> 90 % as determined by SDS-PAGE.

Appearance:Lyophilized powder

Color:White

Resource Download

COA User Guide of Recombinant Proteins

Product Information

Bioactivity

Bioactivity	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Lp-PLA2/PLA2G7 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.3 kDa and the accession number is Q60963.
Species	Mouse
Expression System	HEK293 Cells
Tag	C-His
Accession Number	Q60963
Construction	A DNA sequence encoding the mouse Pla2g7 (NP_038765.2) (Met1-Asn440) was expressed with a polyhistidine tag at the C-terminus. Predicted N terminal: Phe 22
Protein Purity	> 90 % as determined by SDS-PAGE.
Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstituted with sterile deionized water to 0.25 mg/mL. Reconstitution conditions may vary depending on the lot.
Synonyms	R75400, phospholipase A2 group VII
Research Background	Platelet-activating factor acetylhydrolase, also known as 1-alkyl-2-acetylglycerophosphocholine esterase, 2-acetyl-1-alkylglycero-phosphocholine esterase, Group-VIIA phospholipase A2, LDL-associated phospholipase A2, PAF 2-acylhydrolase, PLA2G7 and PAFAH, is a secreted protein that belongs to the AB hydrolase superfamily and Lipase family. PLA2G7 / PAFAH modulates the action of platelet-activating factor (PAF) by hydrolyzing the sn-2 ester bond to yield the biologically inactive lyso-PAF. It has specificity for substrates with a short residue at the sn-2 position. It is inactive against long-chain phospholipids. PLA2G7 / PAFAH is a potent pro- and anti-inflammatory molecule that has been implicated in multiple inflammatory disease processes, including cardiovascular disease. PLA2G7 also represents an important, potentially functional candidate in the pathophysiology of coronary artery disease (CAD). Defects in PLA2G7 are the cause of platelet-activating factor acetylhydrolase deficiency (PLA2G7 deficiency). It is a trait that is present in 27% of Japanese. It could have a significant physiologic effect in the presence of inflammatory bodily responses.

Chemical Properties

Molecular Weight

48.3 kDa (predicted)

Storage & Solubility Information

Shipping	In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.