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Anti-CD155/PVR Antibody (9R440)
😃Good
Catalog No. TMAY-03198
Alias TAGE4, PVS, poliovirus receptor, Necl-5, NECL5, HVED, CD155
Anti-CD155/PVR Antibody (9R440) is a Rabbit antibody targeting CD155/PVR. Anti-CD155/PVR Antibody (9R440) can be used in FCM,ICC/IF.
Anti-CD155/PVR Antibody (9R440)
Anti-CD155/PVR Antibody (9R440)
😃Good
Catalog No. TMAY-03198Alias TAGE4, PVS, poliovirus receptor, Necl-5, NECL5, HVED, CD155
Anti-CD155/PVR Antibody (9R440) is a Rabbit antibody targeting CD155/PVR. Anti-CD155/PVR Antibody (9R440) can be used in FCM,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $292 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CD155/PVR Antibody (9R440) is a Rabbit antibody targeting CD155/PVR. Anti-CD155/PVR Antibody (9R440) can be used in FCM,ICC/IF. |
| Alias | TAGE4, PVS, poliovirus receptor, Necl-5, NECL5, HVED, CD155 |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 9R440 |
| Reactivity | Mouse |
| Verified Activity | 1. Immunofluorescence staining of Mouse PVR(m CD155) in raw264.7 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Rabbit anti-Mouse PVR (m CD155) monoclonal antibody (1:100) at 4°C overnight. Then cells were stained with the Alexa Fluor® 488-conjugated (left panel, captured by laser confocal scanning microscope; right panel, captured by fluorescence microscope) Goat Anti-rabbit IgG secondary antibody, countstained with DAPI (blue). Positive staining was localized to plasma membrane. 2. Flow cytometric analysis of Mouse PVR(CD155) expression on BABL/c splenocytes. Cells were stained with purified anti-Mouse PVR(CD155), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
| Application | FCM,ICC/IF |
| Recommended Dose | ICC-IF: 1:50-1:1000; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD155 / PVR (rM CD155 / PVR; TMPY-00762; NP_081790.1; Met1-Arg345). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | CD155, commonly known as PVR (poliovirus receptor) and Necl-5 (nectin-like molecule-5), is a type I transmembrane single-span glycoprotein, and belongs to the nectins and nectin-like (Necl) subfamily. CD155 was originally identified based on its ability to mediate the cell attachment and entry of poliovirus (PV), an etiologic agent of the central nervous system disease poliomyelitis. The normal cellular function is in the establishment of intercellular adherens junctions between epithelial cells. CD155 may assist in an efficient humoral immune response generated within the intestinal immune system. It has been demonstrated that CD155 can be recognized and bond by DNAM-1 and CD96 which promote the adhesion, migration and NK-cell killing, and thus efficiently prime cell-mediated tumor-specific immunity.Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Unconjugated |
| Others Formats | APC/PerCP/FITC/PE |
| Antibody Types Available | 5 |
| Immunogen | Recombinant Mouse CD155 / PVR protein (TMPY-00762) |
| Antigen Species | Mouse |
| Biology Area | Cancer Drug Targets |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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