Anti-TRAF3 Polyclonal Antibody

Name: Anti-TRAF3 Polyclonal Antibody
Brand: TargetMol
SKU: TMAB-01883
Rating: 4.5 (1 reviews)

(Synonyms: TRAFAMN, TRAF3, TNF receptor-associated factor 3, RING-type E3 ubiquitin transferase TRAF3, LMP1-associated protein 1 (LAP1), CRAF1, CD40-binding protein (CD40BP), CD40 receptor-associated factor 1 (CRAF1), CAP-1) Copy Product Info

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Synonyms: TRAFAMN, TRAF3, TNF receptor-associated factor 3, RING-type E3 ubiquitin transferase TRAF3, LMP1-associated protein 1 (LAP1), CRAF1, CD40-binding protein (CD40BP), CD40 receptor-associated factor 1 (CRAF1), CAP-1

Catalog No. TMAB-01883 Copy Product Info

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Anti-TRAF3 Polyclonal Antibody is a Rabbit antibody targeting TRAF3. Anti-TRAF3 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.

Anti-TRAF3 Polyclonal Antibody

Pack Size	Price	USA Stock	Global Stock
50 μL	$221	7-10 days	7-10 days
100 μL	$374	7-10 days	7-10 days
200 μL	$528	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-TRAF3 Polyclonal Antibody is a Rabbit antibody targeting TRAF3. Anti-TRAF3 Polyclonal Antibody can be used in FCM,IF,IHC-Fr,IHC-P,WB.
Synonyms	TRAFAMN, TRAF3, TNF receptor-associated factor 3, RING-type E3 ubiquitin transferase TRAF3, LMP1-associated protein 1 (LAP1), CRAF1, CD40-binding protein (CD40BP), CD40 receptor-associated factor 1 (CRAF1), CAP-1
Ig Type	IgG
Reactivity	Human,Mouse (predicted:Rat)

Application	FCM IF IHC-Fr IHC-P WB
Recommended Dose	WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
Antibody Type	Polyclonal
Host Species	Rabbit
Tissue Specificity	In adult, highest in brain. Also found in kidney, heart, thymus, spleen, lung, muscle, testis and ovary. Not found in liver.
Construction	Polyclonal Antibody
Purification	Protein A purified
Appearance	Liquid
Formulation	0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Concentration	1 mg/mL
Research Background	The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Three alternatively spliced transcript variants encoding two distinct isoforms have been reported. [provided by RefSeq].

Antigen Details

Immunogen	KLH conjugated synthetic peptide: human TRAF3
Antigen Species	Human
Gene Name	TRAF3
Gene ID	7187
Protein Name	TNF receptor-associated factor 3
Uniprot ID	Q13114
Biology Area	TRAF,TNF,TRAF,TNF Superfamily,SARS Coronavirus,TNF
Function	Adapter protein and signal transducer that links members of the tumor necrosis factor receptor family to different signaling pathways by association with the receptor cytoplasmic domain and kinases. Seems to be involved in activation of NF-kappa-B and JNK and in apoptosis. Is regulated by TANK/ITRAF which competes with TNFRSF5/CD40 for binding. Seems to play a role T-cell dependent immune responses (By similarity).