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IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-359, His & Avi), Biotinylated

(Synonyms: IL-1RAP, IL1RAP, IL-1 RAcP, IL-1 R3, C3orf13) Copy Product Info

Synonyms: IL-1RAP, IL1RAP, IL-1 RAcP, IL-1 R3, C3orf13

Catalog No. TMPK-00331 Copy Product Info
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-359, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is Q9NPH3-1.
Pack SizePriceUSA StockGlobal StockQuantity
5 µg$917-10 days7-10 days
10 µg$1487-10 days7-10 days
20 µg$2457-10 days7-10 days
50 µg$4837-10 days7-10 days
100 µg$8137-10 days7-10 days
200 µg$1,4707-10 days7-10 days
500 µg$3,2507-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Bioactivity
Immobilized Biotinylated Human IL-1R3 at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-IL-1R3 Antibody, hFc Tag with the EC50 of 11.3ng/ml determined by ELISA.
Description
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-359, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is Q9NPH3-1.
Species
Human
Expression System
HEK293 Cells
TagC-His-Avi
Accession NumberQ9NPH3-1
ConstructionSer21-Glu359
Protein Purity
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
Endotoxin< 1.0 EU/μg of the protein as determined by the LAL method.
FormulationLyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
ReconstitutionReconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
SynonymsIL-1RAP, IL1RAP, IL-1 RAcP, IL-1 R3, C3orf13
Research Background
IL-1 Receptor Accessory Protein (IL-1 RAcP), also known as IL-1 R3, is a ubiquitously expressed 70-90 kDa member of the Interleukin-1 receptor family of proteins. It serves as a non-ligand-binding component of the receptors for IL-1 alpha, IL-1 beta, IL-33, and IL-36. IL-1 R3 is a coreceptor for IL1RL2 in the IL-36 signaling system. IL-1 R3 is a coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways.
Chemical Properties
Molecular Weight42 kDa (predicted). Due to glycosylation, the protein migrates to 52-70 kDa based on Tris-Bis PAGE result.
Storage & Solubility Information
ShippingIn general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
StorageIt is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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Related Tags: IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-359, His & Avi), Biotinylated chemical structure | IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-359, His & Avi), Biotinylated molecular weight