Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody

😃Good
Catalog No. TMAC-03431

Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Progesterone Receptor (Ser294). Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody can be used in WB.

Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody

Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody

😃Good
Catalog No. TMAC-03431
Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Progesterone Receptor (Ser294). Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody can be used in WB.
Pack SizePriceAvailabilityQuantity
50 μL$2187-10 days
100 μL$3177-10 days
Add to Cart
Add to Quotation
Bulk & Custom
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Questions
View More

Product Introduction

Bioactivity
Description
Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Progesterone Receptor (Ser294). Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody can be used in WB.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundProgesterone receptors (PRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid,glucocorticoid and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by progesterone receptors is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-kappaB, AP-1 or STAT. Progesterone receptors are found in the female reproductive tract, mammary glands, brain and pituitary gland and receptor expression is induced by estrogen. Well established functions of progesterone receptors include ovulation, implantation, mammary gland development and maintenance of pregnancy. In addition,progesterone, signaling through the progesterone receptor, increases the ventilatory response of the respiratory centers to carbon dioxide and decreases arterial and alveolar PCO2 in the luteal phase of the menstrual cycle and during pregnancy. The human gene encoding the progesterone receptor has been localized to 11q22.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of serine 294 (G-R-S(p)-P-L) derived from Human Progesterone Receptor
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightActual: 99 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Related Tags: buy Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody | purchase Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody | Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody cost | order Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody | Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody molecular weight