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Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody
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Catalog No. TMAC-03431
Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Progesterone Receptor (Ser294). Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody can be used in WB.
Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody
Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody
😃Good
Catalog No. TMAC-03431
Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Progesterone Receptor (Ser294). Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody can be used in WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $218 | 7-10 days | |
| 100 μL | $317 | 7-10 days |
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| Description | Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Progesterone Receptor (Ser294). Anti-Phospho-Progesterone Receptor (Ser294) Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-1000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Progesterone receptors (PRs) are nuclear hormone receptors of the NR3C class, which also includes mineralocorticoid,glucocorticoid and androgen receptors. They exist as homodimers coupled to Hsp90 or HMGB proteins, which are shed upon activation. The major signaling pathway used by progesterone receptors is via direct DNA binding and transcriptional regulation of target genes. They can also signal by binding to other proteins, mainly with transcription factors such as NF-kappaB, AP-1 or STAT. Progesterone receptors are found in the female reproductive tract, mammary glands, brain and pituitary gland and receptor expression is induced by estrogen. Well established functions of progesterone receptors include ovulation, implantation, mammary gland development and maintenance of pregnancy. In addition,progesterone, signaling through the progesterone receptor, increases the ventilatory response of the respiratory centers to carbon dioxide and decreases arterial and alveolar PCO2 in the luteal phase of the menstrual cycle and during pregnancy. The human gene encoding the progesterone receptor has been localized to 11q22. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of serine 294 (G-R-S(p)-P-L) derived from Human Progesterone Receptor |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 99 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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