Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ddUTP (2′,3′-Dideoxyuridine-5′-triphosphate) serves as a selective inhibitor of HIV and AMV reverse transcriptases with Ki values of 0.05 µM for HIV and 1 µM for AMV, respectively. This compound is preferentially incorporated at dTTP sites within the DNA strand, thereby preventing further chain elongation [1].
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Description | ddUTP (2′,3′-Dideoxyuridine-5′-triphosphate) serves as a selective inhibitor of HIV and AMV reverse transcriptases with Ki values of 0.05 µM for HIV and 1 µM for AMV, respectively. This compound is preferentially incorporated at dTTP sites within the DNA strand, thereby preventing further chain elongation [1]. |
Synonyms | 2′,3′-Dideoxyuridine-5′-triphosphate |
Molecular Weight | 448.111 |
Formula | C9H15N2O13P3 |
CAS No. | 84445-38-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
ddUTP 84445-38-5 Microbiology/Virology Reverse Transcriptase 2′,3′-Dideoxyuridine-5′-triphosphate inhibitor inhibit