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Myeloid Cell CD Proteins

Myeloid cells include dendritic cells, monocytes, macrophages, and granulocytes. A dendritic cell (DC) is an antigen-presenting cell of the mammalian immune system. A DC's main function is to process antigen material and present it on the cell surface to the T cells of the immune system. Monocytes are derived from myeloid progenitor cells in the bone marrow. There are three distinct subpopulations of human monocytes: classical, intermediate, and non-classical. Human peripheral blood mononuclear cells are defined based on the expression of cell surface antigens (CD14, CD16, and CD64) and chemokine receptors (CD192 (CCR2) and CX3CR1). Monocytes express leukocyte adhesion molecule (CD226), and the interaction between CD antigen and CD155 regulates monocyte migration. Monocytes play a key role in clearing invading bacteria, viruses, fungi and protozoa, and negatively affect the pathogenesis of inflammatory and degenerative diseases. Macrophages are a type of white blood cell of the innate immune system that engulf and digest pathogens, such as cancer cells, microbes, cellular debris, and foreign substances.They can be identified by their specific expression of proteins such as CD14, CD40, CD11b, CD64, F4/80 (mice)/EMR1 (human), lysozyme M, MAC-1/MAC-3 and CD68.

  • CD40 Ligand Trimer Protein, Human, Recombinant (hFc)
    TMPK-01398
    CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.
    • $418
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  • LAIR2 Protein, Human, Recombinant (hFc)
    TMPJ-00032
    LAIR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 45-55 KDa and the accession number is Q6ISS4.
    • $60
    7-10 days
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  • CD28 Protein, Mouse, Recombinant (hFc & His)
    TMPJ-00099
    T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signals, which are required for their activation. It is the receptor for CD80 and CD86. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. It involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
    • $35
    7-10 days
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  • TREM-2 Protein, Human, Recombinant (Avi & His), Biotinylated
    TMPJ-00115
    TREM-2 Protein, Human, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 30-40 KDa and the accession number is Q9NZC2.
    • $355
    7-10 days
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  • PSGL-1/CD162 Protein, Human, Recombinant (hFc)
    TMPJ-00257
    PSGL-1 (CD162), is a mucintype glycoprotein that plays a key role in leukocyte adhesion. Human PSGL-1 cDNA encodes 412 amino acids (aa). It expressed on neutrophils, monocytes and most lymphocytes. The mature PSGL-1 (aa 42-412) is expressed as a disulfide-linked homodimer that signals intracellularly and promotes integrin activation. PSGL-1 is found on virtually all leukocytes, dendritic cells, platelets, and some endothelial cells. It is primarily responsible for early events in extravasation, especially rolling adhesion of leukocytes to vascular endothelium. Through high affinity, This SLe(x)-type proteoglycanPGSL-1 calcium-dependent interactions with E-, P- and L-selectins, mediates rapid rolling of leukocytes over vascular surfaces during the initial steps in inflammation.
    • $110
    7-10 days
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  • BAFF/TNFSF13B Protein, Human, Recombinant (His)
    TMPJ-00178
    BAFF/TNFSF13B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 22 KDa and the accession number is Q9Y275.
    • $134
    7-10 days
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  • CD32B Protein, Human, Recombinant (His)
    TMPJ-00192
    FcγRIIB is a low affinity receptor that recognizes the Fc portion of IgG. The human CD32 group consists of FcγRIIA, FcγRIIB, and FcγRIIC proteins that share 94-99% sequence identity in their extracellular domains but differ substantially in their transmembrane and cytoplasmic domains. FcγRII protein is expressed on cells of both myeloid and lymphoid lineages as well as on cells of non-hematopoietic origin. FcγRIIB has an intrinsic cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM) and delivers an inhibitory signal upon ligand binding. Ligation of FcγRIIB on B cells down-regulates antibody production and in some circumstances may promote apoptosis. Co-ligation of FcγRIIB on dendritic cells inhibits maturation and blocks cell activation. FcγRIIB may also be a target for monoclonal antibody therapy for malignancies. FcγRIIB plays an important negative-regulating role through modulating the signals from activation receptors.
    • $97
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  • IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated
    TMPJ-00291
    Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to IL6 with low affinity, but does not transduce a signal. Signal activation necessitates an association with IL6ST. Activation may lead to the regulation of the immune response, acute-phase reactions and hematopoiesis. Low concentration of a soluble form of IL6 receptor acts as an agonist of IL6 activity. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
    • $355
    7-10 days
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  • CD36 Protein, Human, Recombinant (hFc)
    TMPJ-00292
    Platelet Glycoprotein 4 (CD36) is an integral membrane glycoprotein that has multiple physiological functions. It is broadly expressed on a variety of cell types including microvascular endothelium, adipocytes, skeletal muscle, epithelial cells of the retina, breast, and intestine, smooth muscle cells, erythroid precursors, platelets, megakaryocytes, dendritic cells, monocytes/macrophages, and microglia. As a member of the scavenger receptor family, CD36 is a multiligand pattern recognition receptor that interacts with a large number of structurally dissimilar ligands, including long chain fatty acid (LCFA), advanced glycation end products (AGE), thrombospondin-1,oxidized lowdensity lipoproteins (oxLDLs), high density lipoprotein (HDL), phosphatidylserine, apoptotic cells, β amyloid fibrils (fAβ), collagens I and IV, and Plasmodium falciparuminfected erythrocytes. CD36 is required for the antiangiogenic effects of thrombospondin-1 in the corneal neovascularization assay. It plays a role in lipid metabolism and has been identified as a fatty acid translocase necessary for the binding and transport of LCFA in cells and tissues.
    • $110
    7-10 days
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  • LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPJ-00321
    LAG-3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 60-70 KDa and the accession number is P18627.
    • $355
    7-10 days
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  • CD16b Protein, Human, Recombinant (hFc & His)
    TMPJ-00419
    Low affinity immunoglobulin gamma Fc region receptor III-B, also known as Fc-gamma RIII-beta, FcR-10, IgG Fc receptor III-1, FCG3, FCGR3, CD16b and FCGR3B. FCGR3B is a GPI-anchor membrane protein and contains two Ig-like C2 type domains. FCGR3B can be expressed in orphonuclear leukocytes and stimulated eosinophils. FCGR3B can interact with INPP5D/SHIP1. FCGR3B localizes in the FCGR gene cluster is a CN polymorphic gene involved in the recruitment of polymorphonuclear neutrophils to sites of inflammation and their activation. FCGR3B may serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
    • $116
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  • CD27/TNFRSF7 Protein, Human, Recombinant (hFc & His)
    TMPJ-00421
    CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1.
    • $47
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  • Endoglin Protein, Human, Recombinant (Trx & His)
    TMPJ-00361
    Endoglin is a single-pass type I membrane protein which restricted to endothelial cells in all tissues except bone marrow. Endoglin as major glycoprotein of vascular endothelium, it has been found on endothelial cells, activated macrophages, fibroblasts, and smooth muscle cells. Furthermore, Homodimer forms a heteromeric complex with the signaling receptors for transforming growth factor-beta: TGFBR1 and/or TGFBR2. It may have an important role in the binding of endothelial cells to integrins and/or other RGD receptors. Defects in ENG are the cause of hereditary hemorrhagic telangiectasia type 1 (HHT1), which is an autosomal dominant multisystemic vascular dysplasia, characterized by recurrent epistaxis, muco-cutaneous telangiectases, gastro-intestinal hemorrhage, and pulmonary (PAVM), cerebral (CAVM) and hepatic arteriovenous malformations.
    • $129
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  • CD30/TNFRSF8 Protein, Human, Recombinant (mFc)
    TMPJ-00343
    CD30/TNFRSF8 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 90-120 KDa and the accession number is P28908.
    • $58
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  • ILDR2 Protein, Human, Recombinant (His)
    TMPJ-00353
    ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasis. The human ILDR2 lumenal domain shares a 99% and 98% homology with the mouse and rat respectively. The human gene encoding ILDR2 is located in a region on Chr1q23–25 that has been associated with type 2 diabetes. ILDR2 plays critical roles in hepatic clearance of lipoproteins and in lipid homeostasis. ILDR2 regulates human dendritic cells (DC2 cells, a subpopulation of polarized DCs that promotes Th2 differentiation). Recent publications reported that ILDR2 displayed negative regulatory functions on human and mouse T cells in various experimental systems. Fusion protein of ILDR2 lumenal domain with an Fc fragment, displays therapeutic effects in collagen-induced arthritis (CIA), a mouse model of rheumatoid arthritis (RA). ILDR2 represents a novel B7-like ligand that exerts negative immune modulation via interaction with a putative counterpart receptor expressed on activated T cells.
    • $86
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  • OX40/TNFRSF4 Protein, Mouse, Recombinant (His)
    TMPJ-00422
    OX40/TNFRSF4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 40 KDa and the accession number is P47741.
    • $116
    7-10 days
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  • CD40 Protein, Cynomolgus, Recombinant (His)
    TMPJ-00634
    CD40 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-30 KDa and the accession number is G7PG38.
    • $116
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  • CTLA-4 Protein, Cynomolgus, Recombinant (His)
    TMPJ-00636
    CTLA-4 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 17-25 KDa and the accession number is G7PL88.
    • $60
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  • PD-L1 Protein, Cynomolgus, Recombinant (His)
    TMPJ-00638
    PD-L1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 32-40 KDa and the accession number is G7PSE7.
    • $110
    7-10 days
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  • BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc)
    TMPJ-01391
    BAFF/TNFSF13B Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with N-mFc tag. The predicted molecular weight is 45-60 KDa and the accession number is Q9WU72.
    • $56
    In Stock
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  • PD-L2 Protein, Human, Recombinant (His & Avi)
    TMPK-00166
    PD-1 ligand 2 (PD-L2) as a second ligand for PD-1 and compare the function and expression of PD-L1 and PD-L2. Engagement of PD-1 by PD-L2 dramatically inhibits T cell receptor (TCR)-mediated proliferation and cytokine production by CD4 T cells. At low antigen concentrations, PD-L2-PD-1 interactions inhibit strong B7-CD28 signals. PD-L2 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.3 kDa and the accession number is Q9BQ51.
    • $324
    7-10 days
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  • BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag)
    TMPK-00176
    B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptors TNFRSF13B/TACI, TNFRSF17/BCMA, and TNFRSF13C/BAFF-R. BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-His-Flag tag. The predicted molecular weight is 52.4 kDa and the accession number is Q9Y275-1.
    • $511
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  • PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
    TMPK-00181
    Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity. PD-1 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is Q02242.
    • $814
    7-10 days
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  • PD-L1 Protein, Human, Recombinant (aa 19-238, His & Avi), Biotinylated
    TMPK-00182
    B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1 Protein, Human, Recombinant (aa 19-238, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.1 kDa and the accession number is Q9NZQ7-1.
    • $814
    7-10 days
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  • CD300A Protein, Human, Recombinant (Avi)
    TMPK-00186
    CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 19.46 kDa and the accession number is Q9UGN4-1.
    • $465
    7-10 days
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  • CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated
    TMPK-00111
    CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. CD28 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 18.2 kDa and the accession number is P10747.
    • $814
    7-10 days
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  • GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His)
    TMPK-00133
    GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 15.4 kDa and the accession number is Q9Y5U5-1.
    • $418
    7-10 days
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  • CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
    TMPK-00080
    CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7.  CD70 is a cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells. CD27 Ligand/CD70 Trimer Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 51.8 kDa and the accession number is P32970-1.
    • $814
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  • ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
    TMPK-00341
    Brain metastasis (BM) in non-small-cell lung cancer (NSCLC) has a very poor prognosis. Recent studies have demonstrated the importance of cell adhesion molecules in tumor metastasis.Elevated levels of ALCAM expression promote BM formation in NSCLC through increased tumor cell dissemination and interaction with the brain endothelial cells. Therefore, ALCAM could be targeted to reduce the occurrence of BM. ALCAM Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57 kDa and the accession number is Q13740-1.
    • $814
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  • LILRB3/CD85a Protein, Human, Recombinant (His & Avi), Biotinylated
    TMPK-00355
    Leukocyte immunoglobulin-like receptor subfamily B (LILRB3), also known as ILT5, LIR3, and CD85a, is an immunoglobulin superfamily member that is involved in immune regulation. Subfamily B members have cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) that inhibit signaling events via phosphatase SHP-1.LILRB3 may act as receptor for class I MHC antigens. Becomes activated upon coligation of LILRB3 and immune receptors, such as FCGR2B and the B-cell receptor. LILRB3/CD85a Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50 kDa and the accession number is O75022-1.
    • $814
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  • Endoglin/CD105 Protein, Human, Recombinant (His & Avi)
    TMPK-00359
    Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response to blood flow, which drive vascular remodeling and establishment of normal vascular morphology during angiogenesis.
    • $418
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  • CD155/PVR Protein, Human, Recombinant (His & Avi)
    TMPK-00260
    CD155 is a cell surface adhesion molecule functioning in tumor cell migration, invasion, and metastasis, and not surprisingly, is also designated as a common tumor-associated antigen. CD155 is also recognized by NK cells to induce their cytotoxicity. CD155 is also commonly referred to as the poliovirus receptor, or PVR.
    • $371
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  • OX40/TNFRSF4 Protein, Human, Recombinant (aa 29-216, His & Avi), Biotinylated
    TMPK-00168
    Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. OX40/TNFRSF4 Protein, Human, Recombinant (aa 29-216, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 23.2 kDa and the accession number is P43489.
    • $814
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  • SLAMF7 Protein, Human, Recombinant (His & Avi)
    TMPK-00225
    SLAMF7 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.3 kDa and the accession number is Q9NQ25-1.
    • $313
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  • CD31/PECAM-1 Protein, Human, Recombinant (aa 28-601, His)
    TMPK-00834
    Platelet endothelial cell adhesion molecule 1 (PECAM-1) is an adhesion and signaling receptor that is expressed on endothelial and hematopoietic cells and plays important roles in angiogenesis, vascular permeability, and regulation of cellular responsiveness. CD31/PECAM-1 Protein, Human, Recombinant (aa 28-601, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 65.6 kDa and the accession number is P16284-1.
    • $302
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  • OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi)
    TMPK-00463
    Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. OX40/TNFRSF4 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 24.2 kDa and the accession number is P47741.
    • $324
    7-10 days
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  • CD200 Protein, Cynomolgus, Recombinant (His)
    TMPK-00476
    CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with asthma. Moreover, pharmacological modulation of CD200 receptors was shown to improve clinical and inflammatory outcomes of preclinical asthma models. CD200 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 23.66 kDa and the accession number is A0A2K5TQS2.
    • $487
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  • CD300A Protein, Cynomolgus, Recombinant (Avi)
    TMPK-00559
    CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Cynomolgus, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 19.44 kDa and the accession number is A0A7N9CE79.
    • $605
    7-10 days
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  • CD300A Protein, Cynomolgus, Recombinant (His)
    TMPK-00561
    CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 18.73 kDa and the accession number is A0A7N9CE79.
    • $487
    7-10 days
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  • CD31/PECAM-1 Protein, Cynomolgus, Recombinant (His)
    TMPK-00562
    Platelet endothelial cell adhesion molecule 1 (PECAM-1) is an adhesion and signaling receptor that is expressed on endothelial and hematopoietic cells and plays important roles in angiogenesis, vascular permeability, and regulation of cellular responsiveness. CD31/PECAM-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 65.30 kDa and the accession number is A0A7N9CHZ3.
    • $487
    7-10 days
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  • PSGL-1/CD162 Protein, Cynomolgus, Recombinant (His)
    TMPK-00565
    P-selectin glycoprotein ligand-1 (PSGL-1) has long been studied as an adhesion molecule involved in immune cell trafficking and is recognized as a regulator of many facets of immune responses by myeloid cells. PSGL-1 also regulates T cell migration during homeostasis and inflammatory settings. PSGL-1/CD162 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 34.57 kDa and the accession number is A0A7N9CVJ8.
    • $487
    7-10 days
    Size
    QTY
  • CD300A Protein, Cynomolgus, Recombinant (Avi), Biotinylated
    TMPK-00560
    CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Cynomolgus, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 19.44 kDa and the accession number is A0A7N9CE79.
    • $932
    7-10 days
    Size
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  • GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His)
    TMPK-01086
    GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway. GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q8C4K3.
    • $418
    7-10 days
    Size
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  • CD28 Protein, Canine, Recombinant (His)
    TMPK-01176
    CD28 is the receptor for CD80 (B7-1) and CD86 (B7-2) proteins.When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells. CD28 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 16.7 kDa and the accession number is Q9GKP3.
    • $465
    7-10 days
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  • CD36 Protein, Cynomolgus, Recombinant (His)
    TMPK-00292
    CD36 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 47.67 kDa and the accession number is Q4R6B4.
    • $487
    7-10 days
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  • LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 1-474, hFc)
    TMPK-00682
    LILRB1/CD85j/ILT2 Protein, Rhesus macaque, Recombinant (aa 1-474, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 75.2 kDa and the accession number is NP_001035762.2.
    • $465
    7-10 days
    Size
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  • CD200 Protein, Mouse, Recombinant (aa 31-232, His)
    TMPK-00733
    CD200 and its receptors are highly expressed in the lung, on epithelial cells and leukocytes, and emerging evidence links dysregulation of the CD200 pathway with asthma. Moreover, pharmacological modulation of CD200 receptors was shown to improve clinical and inflammatory outcomes of preclinical asthma models. CD200 Protein, Mouse, Recombinant (aa 31-232, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 23.6 kDa and the accession number is O54901.
    • $302
    7-10 days
    Size
    QTY
  • BAFFR/TNFRSF13C Protein, Cynomolgus, Recombinant (His)
    TMPK-01254
    BAFF binds to three TNF receptor superfamily members: B-cell maturation antigen (BCMA / TNFRSF17), transmembrane activator and calcium-modulator and cyclophilin ligand interactor (TACI/TNFRSF13B) and BAFF receptor (BAFF R/BR3/TNFRSF13C). These receptors are type III transmembrane proteins that lack a signal peptide. Whereas TACI and BCMA bind BAFF and another TNF superfamily ligand, APRIL (a proliferation-inducing ligand), BAFF R selectively binds BAFF.
    • $487
    7-10 days
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  • CD3 epsilon/CD3e 1-27 peptide Protein, Cynomolgus, Recombinant (hFc & Avi)
    TMPK-01350
    CD3E, is a single-pass type I membrane protein.CD3 (cluster of differentiation 3) T cell co-receptor helps to activate both the cytotoxic T cell (CD8 naive T cells) and also T helper cells (CD4 naive T cells). It consists of a protein complex and is composed of four distinct chains. In mammals, the complex contains a CD3γ chain, a CD3δ chain, and two CD3ε chains. CD3 epsilon/CD3e 1-27 peptide Protein, Cynomolgus, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with C-hFc-Avi tag. The predicted molecular weight is 31.3 kDa and the accession number is Q95LI5.2.
    • $581
    7-10 days
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  • CD147 Protein, Human, Recombinant (aa 138-323, hFc)
    TMPH-00998
    CD147 Protein, Human, Recombinant (aa 138-323, hFc) is expressed in HEK293.
    • $368
    20 days
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