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Lipoxin B4 methyl ester

Name: Lipoxin B4 methyl ester
Brand: TargetMol
SKU: T38308
Rating: 4.5 (1 reviews)

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Catalog No. T38308Cas No. 97589-07-6

Lipoxin B4 (LXB4) methyl ester is a lipid-soluble prodrug form of the transcellular metabolite LXB4, which is a positional isomer of LXA4 produced by the metabolism of 15-HETE or 15-HpETE by human leukocytes. At 100 nM, LXB4 inhibits polymorphonuclear leukocyte (PMN) migration stimulated by leukotriene B4 and inhibits LTB4-induced adhesion of PMNs with an IC50 of 0.3 nM.

Lipoxin B4 methyl ester

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Catalog No. T38308Cas No. 97589-07-6

Pack Size	Price	Availability
25 μg	$993	35 days
50 μg	$1,870	35 days
100 μg	$3,550	35 days

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	366.498
Formula	C₂₁H₃₄O₅
Cas No.	97589-07-6

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

PBS (pH 7.2): 1 mg/mL (2.73 mM), Sonication is recommended.

Ethanol: 50 mg/mL (136.43 mM), Sonication is recommended.

DMF: 50 mg/mL (136.43 mM), Sonication is recommended.

Solution Preparation Table

PBS (pH 7.2)/Ethanol/DMF

	1mg	5mg	10mg	50mg
1 mM	2.7285 mL	13.6426 mL	27.2853 mL	136.4264 mL

Ethanol/DMF

	1mg	5mg	10mg	50mg
5 mM	0.5457 mL	2.7285 mL	5.4571 mL	27.2853 mL
10 mM	0.2729 mL	1.3643 mL	2.7285 mL	13.6426 mL
20 mM	0.1364 mL	0.6821 mL	1.3643 mL	6.8213 mL
50 mM	0.0546 mL	0.2729 mL	0.5457 mL	2.7285 mL
100 mM	0.0273 mL	0.1364 mL	0.2729 mL	1.3643 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Lipoxin B-4 methyl esterLipoxin B4 methyl ester