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Anti-LAMP1/CD107a Antibody
(Synonyms: SAR-428926 Antibody) Copy Product Info
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Synonyms: SAR-428926 Antibody
Catalog No. T9901A-805 Copy Product Info
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Anti-LAMP1/CD107a Antibody (SAR-428926 antibody) is a humanized monoclonal antibody targeting Lysosomal-Associated Membrane Protein 1 (LAMP1/CD107a). LAMP1 is typically located on lysosomal membranes but is highly expressed on the surface of various solid tumor cells. Serving as the targeting moiety of the antibody-drug conjugate (ADC) SAR-428926, this antibody specifically binds to surface-expressed LAMP1, mediating the internalization of the ADC and the release of a potent maytansinoid cytotoxic payload. This targeting strategy demonstrates outstanding anti-tumor efficacy in patient-derived xenograft (PDX) models of solid tumors, effectively inhibiting tumor growth.
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-LAMP1/CD107a Antibody (SAR-428926 antibody) is a humanized monoclonal antibody targeting Lysosomal-Associated Membrane Protein 1 (LAMP1/CD107a). LAMP1 is typically located on lysosomal membranes but is highly expressed on the surface of various solid tumor cells. Serving as the targeting moiety of the antibody-drug conjugate (ADC) SAR-428926, this antibody specifically binds to surface-expressed LAMP1, mediating the internalization of the ADC and the release of a potent maytansinoid cytotoxic payload. This targeting strategy demonstrates outstanding anti-tumor efficacy in patient-derived xenograft (PDX) models of solid tumors, effectively inhibiting tumor growth. |
| Synonyms | SAR-428926 Antibody |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | LAMP1/CD107a |
| Isotype | IgG1 |
| Storage | Store at low temperature Store at -20°C Shipping with blue ice/Shipping at ambient temperature. |
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Related Tags: Anti-LAMP1/CD107a Antibody chemical structure
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