SUMF1 Protein, Human, Recombinant (His)

Name: SUMF1 Protein, Human, Recombinant (His)
Brand: TargetMol
SKU: TMPJ-01229
Rating: 4.5 (1 reviews)

(Synonyms: SUMF1, Sulfatase-Modifying Factor 1, FGE, C-α-Formylglycine-Generating Enzyme 1, C-Alpha-Formylglycine-Generating Enzyme 1) Copy Product Info

Synonyms: SUMF1, Sulfatase-Modifying Factor 1, FGE, C-α-Formylglycine-Generating Enzyme 1, C-Alpha-Formylglycine-Generating Enzyme 1

Catalog No. TMPJ-01229 Copy Product Info

Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein. SUMF1 is a Ca2+-binging member of the sulfatase-modifying factor family. SUMF1 is a soluble ER lumenal glycoprotein, it converts inactive sulfatases into an active form by transforming a catalytic site cysteine into a formylglycine residue. In the ER, SUMF1 can exist as either a monomer, or a disulfide-linked homodimer or a heterodimer with SUMF2. Three splice isoforms are known.

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Pack Size	Price	USA Stock	Global Stock
10 µg	$129	7-10 days	7-10 days
20 µg	$198	7-10 days	7-10 days
50 µg	$390	7-10 days	7-10 days
100 µg	$626	7-10 days	7-10 days
200 µg	$987	7-10 days	7-10 days
500 µg	$1,900	7-10 days	7-10 days
1 mg	$2,730	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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User Guide of Recombinant Proteins

Product Introduction

Bioactivity

Bioactivity	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
Description	Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein. SUMF1 is a Ca2+-binging member of the sulfatase-modifying factor family. SUMF1 is a soluble ER lumenal glycoprotein, it converts inactive sulfatases into an active form by transforming a catalytic site cysteine into a formylglycine residue. In the ER, SUMF1 can exist as either a monomer, or a disulfide-linked homodimer or a heterodimer with SUMF2. Three splice isoforms are known.
Species	Human
Expression System	HEK293 Cells
Tag	C-6xHis
Accession Number	Q8NBK3
Amino Acid	Ser34-Asp374
Construction	Ser34-Asp374
Protein Purity	Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxin	< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation	Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 2 mM CaCl<sub>2</sub>, 10% Glycerol, pH 7.5.
Synonyms	SUMF1, Sulfatase-Modifying Factor 1, FGE, C-α-Formylglycine-Generating Enzyme 1, C-Alpha-Formylglycine-Generating Enzyme 1
Research Background	Human Sulfatase Modifying Factor 1 (SUMF1) is a 42kDa protein. SUMF1 is a Ca2+-binging member of the sulfatase-modifying factor family. SUMF1 is a soluble ER lumenal glycoprotein, it converts inactive sulfatases into an active form by transforming a catalytic site cysteine into a formylglycine residue. In the ER, SUMF1 can exist as either a monomer, or a disulfide-linked homodimer or a heterodimer with SUMF2. Three splice isoforms are known.

Chemical Properties

Molecular Weight

38-42 KDa (reducing condition)

Storage & Solubility Information

Shipping	Proteins are shipped with blue ice.
Storage	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.