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HIV-1 gp120 is an envelope glycoprotein derived from the surface subunit of the HIV-1 Env protein. It plays a critical role in viral entry by binding to the CD4 receptor and CCR5/CXCR4 co-receptors on host cells. Recombinant gp120 is commonly used in studies of HIV pathogenesis, neutralizing antibody screening, vaccine development, and receptor-ligand interaction assays.

| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 μg | $32 | 7-10 days | |
| 10 μg | $47 | 7-10 days | |
| 20 μg | $75 | 7-10 days | |
| 50 μg | $148 | 7-10 days | |
| 100 μg | $256 | 7-10 days | |
| 200 μg | $449 | 7-10 days | |
| 500 μg | $955 | 7-10 days | |
| 1 mg | $1,370 | 7-10 days |
| Biological Activity | Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first. |
| Description | HIV-1 gp120 is an envelope glycoprotein derived from the surface subunit of the HIV-1 Env protein. It plays a critical role in viral entry by binding to the CD4 receptor and CCR5/CXCR4 co-receptors on host cells. Recombinant gp120 is commonly used in studies of HIV pathogenesis, neutralizing antibody screening, vaccine development, and receptor-ligand interaction assays. |
| Species | HIV |
| Expression System | HEK293 Cells |
| Tag | C-8xHis |
| Accession Number | Q9DKG6 |
| Synonyms | Surface protein gp120,Glycoprotein 120,Envelope glycoprotein gp120 |
| Amino Acid | Met1-Glu498 |
| Construction | Met1-Glu498 |
| Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
| Molecular Weight | 90-140 KDa (reducing condition) |
| Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| Stability & Storage | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
| Shipping | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| Research Background | HIV-1 gp120 is an envelope glycoprotein derived from the surface subunit of the HIV-1 Env protein. It plays a critical role in viral entry by binding to the CD4 receptor and CCR5/CXCR4 co-receptors on host cells. Recombinant gp120 is commonly used in studies of HIV pathogenesis, neutralizing antibody screening, vaccine development, and receptor-ligand interaction assays. |

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