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TOPRelated productsBioactivityChemical infoStorage&SolubilityCalculator

(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid

🥰Excellent
Catalog No. TN7074Cas No. 38489-76-8

(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid displays EC50 values of 73.5 μM against T. cruzi. trypomastigotes.

(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid

(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid

🥰Excellent
Purity: 99.87%
Catalog No. TN7074Cas No. 38489-76-8
(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid displays EC50 values of 73.5 μM against T. cruzi. trypomastigotes.
Pack SizePriceAvailabilityQuantity
1 mg$75In Stock
5 mg$183In Stock
10 mg$288In Stock
25 mg$489In Stock
50 mgPreferentialIn Stock
1 mL x 10 mM (in DMSO)$146In Stock
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Purity:99.87%
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Product Introduction

Bioactivity
Description
(2E)-3-(1,3-Benzodioxol-5-yl)-2-propenoic acid displays EC50 values of 73.5 μM against T. cruzi. trypomastigotes.
Targets&IC50
T. cruzi:73.5 μM(EC50)
Chemical Properties
Molecular Weight192.17
FormulaC10H8O4
Cas No.38489-76-8
SmilesOC(=O)\C=C\C1=CC2=C(OCO2)C=C1
Relative Density.1.31g/cm3
ColorWhite
AppearanceSolid
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (260.19 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM5.2037 mL26.0186 mL52.0373 mL260.1863 mL
5 mM1.0407 mL5.2037 mL10.4075 mL52.0373 mL
10 mM0.5204 mL2.6019 mL5.2037 mL26.0186 mL
20 mM0.2602 mL1.3009 mL2.6019 mL13.0093 mL
50 mM0.1041 mL0.5204 mL1.0407 mL5.2037 mL
100 mM0.0520 mL0.2602 mL0.5204 mL2.6019 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
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Keywords

Trypanosoma cruzistem barkInhibitorinhibitEndogenous MetaboliteBrombya platynema3-(1,3-Benzodioxol-5-yl)-2-propenoic acid(2E)3(1,3Benzodioxol5yl)2propenoic acid(2E) 3 (1,3 Benzodioxol 5 yl) 2 propenoic acid
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