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Anti-PHGDH Antibody (9Z346)
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Catalog No. TMAY-02517
Alias SERA, phosphoglycerate dehydrogenase, PHGDHD, PGDH, PGD, PGAD, PDG, NLS1, NLS, HEL-S-113, 3-PGDH, 3PGDH
Anti-PHGDH Antibody (9Z346) is a Mouse antibody targeting PHGDH. Anti-PHGDH Antibody (9Z346) can be used in ELISA.
Anti-PHGDH Antibody (9Z346)
Anti-PHGDH Antibody (9Z346)
😃Good
Catalog No. TMAY-02517Alias SERA, phosphoglycerate dehydrogenase, PHGDHD, PGDH, PGD, PGAD, PDG, NLS1, NLS, HEL-S-113, 3-PGDH, 3PGDH
Anti-PHGDH Antibody (9Z346) is a Mouse antibody targeting PHGDH. Anti-PHGDH Antibody (9Z346) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Mouse Monoclonal Application: ELISA Reactivity: Human |
| Alias | SERA, phosphoglycerate dehydrogenase, PHGDHD, PGDH, PGD, PGAD, PDG, NLS1, NLS, HEL-S-113, 3-PGDH, 3PGDH |
| Ig Type | Mouse IgG2b |
| Clone | 9Z346 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PGDH / PHGDH (rh PGDH / PHGDH; TMPY-02801; O43175; Met1-Phe533). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the substrate binding and the catalytic reaction, and thus to be targets for site-directed mutagenesis. A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related. PHGDH catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor. Overexpression of PHGDH may cause certain breast cancers. Defects in PHGDH are the cause of phosphoglycerate dehydrogenase deficiency which is characterized by congenital microcephaly, psychomotor retardation, and seizures. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human PGDH / PHGDH protein (TMPY-02801) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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