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Diosmetin-7-O-β-D-glucopyranoside
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Catalog No. T4S0692Cas No. 20126-59-4
Alias Eridictiol, Diosmetin-7-O-beta-D-glucopyranoside
Diosmetin-7-O-β-D-glucopyranoside (Eridictiol) exhibits antioxidant activity.
Diosmetin-7-O-β-D-glucopyranoside
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Purity: 99.44%
Catalog No. T4S0692Alias Eridictiol, Diosmetin-7-O-beta-D-glucopyranosideCas No. 20126-59-4
Diosmetin-7-O-β-D-glucopyranoside (Eridictiol) exhibits antioxidant activity.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | $68 | In Stock | In Stock | |
| 2 mg | $98 | In Stock | In Stock | |
| 5 mg | $163 | In Stock | In Stock | |
| 10 mg | $272 | In Stock | In Stock | |
| 25 mg | $458 | In Stock | In Stock | |
| 50 mg | $663 | In Stock | In Stock | |
| 100 mg | $927 | - | In Stock | |
| 200 mg | $1,230 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $166 | In Stock | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Batch Information
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Purity:99.44%
Appearance:Solid
Color:White to Yellow
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Product Introduction
Diosmetin-7-O-β-D-glucopyranoside AI Summary
Diosmetin-7-O-β-D-glucopyranoside demonstrates a diverse range of bioactivities, particularly as an inhibitor of various enzymes. It exhibits an inhibitory effect on cow milk xanthine oxidase with an inhibition rate of 28.9% at 50 µg/mL, indicating potential in xanthine oxidase inhibition. The compound also inhibits the human IDH1 R132H mutant and human IDH1 enzyme activity in vitro with inhibition levels of 111.5% and 107.5% in specific enzyme assays involving NADPH and NADP+. In addition, it shows bioactivity as an LSD1 inhibitor with an IC50 value of 21,830 nM, demonstrating moderate potency. Against the human recombinant full-length PTP1B enzyme, Diosmetin-7-O-β-D-glucopyranoside displays inhibition percentages of 27.74%, 23.36%, and 29.79% at 1 µM, 5 µM, and 10 µM, respectively. However, it demonstrates weak inhibitory activity against baker's yeast alpha-glucosidase with an IC50 value exceeding 100,000 nM. Furthermore, the compound exhibits anti-inflammatory properties by decreasing PGE2 production in LPS-stimulated mouse RAW264.7 cells, though its potency is relatively low with an IC50 value greater than 50,000 nM..
Note: Summary generated by AI. Data source: ChEMBL 
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | Diosmetin-7-O-β-D-glucopyranoside (Eridictiol) exhibits antioxidant activity. |
| Synonyms | Eridictiol, Diosmetin-7-O-beta-D-glucopyranoside |
| Molecular Weight | 462.4 |
| Formula | C22H22O11 |
| Cas No. | 20126-59-4 |
| Smiles | COc1ccc(cc1O)-c1cc(=O)c2c(O)cc(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc2o1 |
| Relative Density. | 1.609 g/cm3 |
| Storage | keep away from direct sunlight | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | ||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 45 mg/mL (97.32 mM), Sonication is recommended.  | ||||||||||||||||||||||||||||||
Solution Preparation Table | |||||||||||||||||||||||||||||||
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Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Keywords
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