Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Cyclic diadenylate (c-di-AMP) sodium functions as a STING agonist by binding to the STING transmembrane protein, thus activating the TBK3-IRF3 signaling pathway. This activation prompts the production of type I IFN and TNF. Additionally, c-di-AMP sodium serves as a bacterial second messenger in Gram-positive bacteria, where it plays crucial roles in regulating cell growth, survival, and virulence, as well as the host immune response. It also acts as a potent mucosal adjuvant by stimulating both humoral and cellular responses [1] [2] [3] [4].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 μg | 35 days | $ 455.00 | |
1 mg | 35 days | $ 770.00 | |
5 mg | 35 days | $ 2,910.00 |
Description | Cyclic diadenylate (c-di-AMP) sodium functions as a STING agonist by binding to the STING transmembrane protein, thus activating the TBK3-IRF3 signaling pathway. This activation prompts the production of type I IFN and TNF. Additionally, c-di-AMP sodium serves as a bacterial second messenger in Gram-positive bacteria, where it plays crucial roles in regulating cell growth, survival, and virulence, as well as the host immune response. It also acts as a potent mucosal adjuvant by stimulating both humoral and cellular responses [1] [2] [3] [4]. |
Molecular Weight | 702.38 |
Formula | C20H22N10Na2O12P2 |
CAS No. | 2734909-87-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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c-di-AMP disodium 2734909-87-4 inhibitor inhibit