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Apilimod

Name: Apilimod
Brand: TargetMol
SKU: T2018
Price: 43 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T2018Cas No. 541550-19-0

Alias STA 5326

Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.

Apilimod

🥰Excellent

Purity: 99.89%

Catalog No. T2018Alias STA 5326Cas No. 541550-19-0

Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.

Pack Size	Price	Availability
5 mg	$43	In Stock
10 mg	$68	In Stock
25 mg	$81	In Stock
50 mg	$97	In Stock
100 mg	$158	In Stock
1 mL x 10 mM (in DMSO)	$48	In Stock

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Batch Information

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Purity:99.89%

Resource Download

COA LCMS HNMR HPLC

Product Introduction

Bioactivity

Description	Apilimod (STA 5326) inhibits the production of IL-12 and IL-23 and reduces dendritic cell infiltration in psoriasis.
Targets&IC50	PIKfyve:14 nM
Synonyms	STA 5326

Chemical Properties

Molecular Weight	418.49
Formula	C₂₃H₂₆N₆O₂
Cas No.	541550-19-0
Smiles	Cc1cccc(\C=N\Nc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1
Relative Density.	1.24
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 200 mg/mL (477.91 mM), Sonication and heating are recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3895 mL	11.9477 mL	23.8954 mL	119.4772 mL
5 mM	0.4779 mL	2.3895 mL	4.7791 mL	23.8954 mL
10 mM	0.2390 mL	1.1948 mL	2.3895 mL	11.9477 mL
20 mM	0.1195 mL	0.5974 mL	1.1948 mL	5.9739 mL
50 mM	0.0478 mL	0.2390 mL	0.4779 mL	2.3895 mL
100 mM	0.0239 mL	0.1195 mL	0.2390 mL	1.1948 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc