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Anti-IL-1RAPL1 Antibody (2J77) is a Mouse antibody targeting IL-1RAPL1. Anti-IL-1RAPL1 Antibody (2J77) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-IL-1RAPL1 Antibody (2J77) is a Mouse antibody targeting IL-1RAPL1. Anti-IL-1RAPL1 Antibody (2J77) can be used in ELISA. |
Alias | TIGIRR-2, OPHN4, MRX34, interleukin 1 receptor accessory protein-like 1, IL1RAPL, IL1R8, C030039N24, 6330532G10Rik |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 2J77 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-1R8 / IL1RAPL1 (rh IL-1R8 / IL1RAPL1; TMPY-01036; NP_055086.1; Met 1-Leu 354). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a member of the interleukin-1 receptor family. The protein structurally comprises three extracellular immunoglobulin domains, which presumably mediate binding of an as yet unidentified ligand, a transmembrane region, and an intracellular domain, which is likely to enable signaling via the NFkB pathway. The means of signaling is almost certain to be identical to that used by the IL1R family and the more distally related Toll protein. L1RAPL1 protein physically interacts via its 150 aa C-terminal domain with neuronal calcium sensor-1 (NCS-1), a protein widely expressed in neurons and the related chromaffin and PC12 cells. IL1RAPL1 is an integral membrane protein responsible for a nonsyndromic form of mental retardation (MR). It is suggested to affect the human cognitive ability to some extent, especially the memory and concentration capability. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human IL-1R8 / IL1RAPL1 protein (TMPY-01036) |
Antigen Species | Human |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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