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Livin/BIRC7 Protein, Human, Recombinant (His)

Catalog No. TMPY-04118
Synonyms: MLIAP, baculoviral IAP repeat containing 7, RNF50, KIAP, ML-IAP, LIVIN

BIRC7, a new member of inhibitor of the apoptosis protein family, is expressed in fetal tissues and most solid tumors in humans. BIRC7/livin expression is a novel prognostic marker in adult acute leukemia. Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family, which are involved in tumor development through the inhibition of caspases. Livin/BIRC7 is specifically over-expressed in ACC, suggesting that it might be involved in adrenocortical tumorigenesis and represent a new molecular marker of malignancy.

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Livin/BIRC7 Protein, Human, Recombinant (His)
Pack Size Availability Price/USD Quantity
100 μg 5 days $ 600.00
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Biological Description
Technical Params
Product Properties
Description BIRC7, a new member of inhibitor of the apoptosis protein family, is expressed in fetal tissues and most solid tumors in humans. BIRC7/livin expression is a novel prognostic marker in adult acute leukemia. Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family, which are involved in tumor development through the inhibition of caspases. Livin/BIRC7 is specifically over-expressed in ACC, suggesting that it might be involved in adrenocortical tumorigenesis and represent a new molecular marker of malignancy.
Species Human
Expression System E. coli
Tag His
Accession Number AAH14475.1
Synonyms MLIAP, baculoviral IAP repeat containing 7, RNF50, KIAP, ML-IAP, LIVIN
Construction A DNA sequence encoding the human BIRC7 (AAH14475.1) (Met1-Ser298) was expressed with a polyhistide tag at the C-terminus.
Protein Purity > 85 % as determined by SDS-PAGE
Molecular Weight Approxiamtely 33.6 kDa
Endotoxin Please contact us for more information.
Formulation Supplied as sterile 50 mM Tris, 200 mM NaCl, pH 8.0. Please contact us for any concerns or special requirements. Please refer to the specific buffer information in the hard copy of CoA.
Reconstitution A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Stability & Storage

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Shipping

Solution. It is shipped out with blue ice.

Research Background BIRC7, a new member of inhibitor of the apoptosis protein family, is expressed in fetal tissues and most solid tumors in humans. BIRC7/livin expression is a novel prognostic marker in adult acute leukemia. Livin/BIRC7 is a member of the inhibitors of apoptosis proteins family, which are involved in tumor development through the inhibition of caspases. Livin/BIRC7 is specifically over-expressed in ACC, suggesting that it might be involved in adrenocortical tumorigenesis and represent a new molecular marker of malignancy.

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Keywords

Livin/BIRC7 Protein, Human, Recombinant (His) MLIAP RNF 50 baculoviral IAP repeat containing 7 RNF50 KIAP RNF-50 ML-IAP LIVIN recombinant recombinant-proteins proteins protein

 

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