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Vapitadine (Synonyms: R 129160)

Catalog No. T29096L Copy Product Info
Purity: 99.86%
🥰Excellent
Vapitadine is a non-sedative antihistamine compound that relieves itching caused by atopic dermatitis.

Vapitadine

Copy Product Info
🥰Excellent
Catalog No. T29096L
Synonyms R 129160

Vapitadine is a non-sedative antihistamine compound that relieves itching caused by atopic dermatitis.

Vapitadine
Cas No. 793655-64-8
Pack SizePriceUSA StockGlobal StockQuantity
1 mg$195-In Stock
5 mg$483In StockIn Stock
10 mg$692-In Stock
25 mg$1,080-In Stock
50 mg$2,073-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:99.86%
Appearance:Solid
Color:White to Yellow
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Product Introduction

Vapitadine AI Summary
Vapitadine exhibits antiviral activity against SARS-CoV-2, as evidenced by its ability to inhibit SARS-CoV-2 induced cytotoxicity in VERO-6 cells. The compound shows an IC50 value greater than 20,000 nM in one assay and greater than 19,952.62 nM in another, indicating a moderate to weak inhibitory effect on virus-induced cytotoxicity under these experimental conditions..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Vapitadine is a non-sedative antihistamine compound that relieves itching caused by atopic dermatitis.
SynonymsR 129160
Chemical Properties
Molecular Weight296.37
FormulaC17H20N4O
Cas No.793655-64-8
SmilesO=C(N)C1=CN=C2N1CCC=3C=CC=CC3C24CCNCC4
Relative Density.1.39 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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