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Anti-GDF-15 Antibody-HRP (7H179)

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Catalog No. TMAY-01351H
Alias PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15

Anti-GDF-15 Antibody-HRP (7H179) is a HRP-conjugated Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody-HRP (7H179) can be used in ELISA.

Anti-GDF-15 Antibody-HRP (7H179)

Anti-GDF-15 Antibody-HRP (7H179)

😃Good
Catalog No. TMAY-01351HAlias PTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15
Anti-GDF-15 Antibody-HRP (7H179) is a HRP-conjugated Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody-HRP (7H179) can be used in ELISA.
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100 μg$294 7-10 days
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Product Introduction

Bioactivity
Description
Anti-GDF-15 Antibody-HRP (7H179) is a HRP-conjugated Mouse antibody targeting GDF-15. Anti-GDF-15 Antibody-HRP (7H179) can be used in ELISA.
AliasPTGFB, PLAB, PDF, NAG-1, MIC-1, MIC1, growth differentiation factor 15, GDF-15
Ig Type
Monoclonal Mouse IgG1
Clone
7H179
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 0.1-1 μg/ml
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human GDF15/MIC-1 (rh GDF15/MIC-1; TMPY-04727; NP_004855.2; Ala197-Ile308). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundGrowth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not expressed in the normal adult heart but is induced in response to conditions that promote hypertrophy and dilated cardiomyopathy and it is expressed highly in liver. GDF-15 / GDF15 has a role in regulating inflammatory and apoptotic pathways in injured tissues and during disease processes. GDF-15 / GDF15 is synthesized as precursor molecules that are processed at a dibasic cleavage site to release C-terminal domains containing a characteristic motif of 7 conserved cysteines in the mature protein. GDF-15 / GDF15 overexpression arising from an expanded erythroid compartment contributes to iron overload in thalassemia syndromes by inhibiting hepcidin expression.
Related Conjugates and Formulations
Conjucates
HRP
Others Formats
Unconjugated
Antibody Types Available
2
Antigen Details
Immunogen
Recombinant Human GDF15/MIC-1 Protein (TMPY-04727)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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