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Propargylcholine

Catalog No. T38173 CAS 111755-76-1

Synonyms: Propargylcholine (bromide)

Propargylcholine is an alkyne-modified choline analog and inhibits choline catabolism at the level of Dgc enzyme-catalyzed dimethylglycine demethylation in Pseudomonas aeruginosa.

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Propargylcholine, CAS 111755-76-1

Pack Size	Availability	Price/USD
10 mg	In stock	$ 41.00
25 mg	In stock	$ 91.00
50 mg	In stock	$ 148.00
100 mg	In stock	$ 282.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Propargylcholine is an alkyne-modified choline analog and inhibits choline catabolism at the level of Dgc enzyme-catalyzed dimethylglycine demethylation in Pseudomonas aeruginosa.

Synonyms	Propargylcholine (bromide)
Molecular Weight	208.1
Formula	C7H14BrNO
CAS No.	111755-76-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

DMF: 30 mg/ml

Ethanol: 30 mg/ml

DMSO: 30 mg/ml

PBS (pH 7.2): 10 mg/ml

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Fitzsimmons LF, et al. Small-molecule inhibition of choline catabolism in Pseudomonas aeruginosa and other aerobic choline-catabolizing bacteria. Appl Environ Microbiol. 2011 Jul;77(13):4383-9. 2. Snodgrass CJ, et al. Conserved ion and amino acid transporters identified as phosphorylcholine-modified N-glycoproteins by metabolic labeling with propargylcholine in Caenorhabditis elegans cells. Glycobiology. 2015 Apr;25(4):403-11.

Related compound libraries

This product is contained In the following compound libraries：

Bioactive Compounds Library Max Bioactive Compound Library Anti-Bacterial Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Propargylcholine 111755-76-1 Microbiology/Virology Antibacterial Propargylcholine (bromide) inhibitor inhibit

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