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Propargylcholine

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Catalog No. T38173Cas No. 111755-76-1
Alias Propargylcholine (bromide)

Propargylcholine (Propargylcholine (bromide)) is an alkyne-modified choline analog and inhibits choline catabolism at the level of Dgc enzyme-catalyzed dimethylglycine demethylation in Pseudomonas aeruginosa.

Propargylcholine

Propargylcholine

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Purity: 99.70%
Catalog No. T38173Alias Propargylcholine (bromide)Cas No. 111755-76-1
Propargylcholine (Propargylcholine (bromide)) is an alkyne-modified choline analog and inhibits choline catabolism at the level of Dgc enzyme-catalyzed dimethylglycine demethylation in Pseudomonas aeruginosa.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
5 mg$30-In Stock
10 mg$40In StockIn Stock
25 mg$89In StockIn Stock
50 mg$147In StockIn Stock
100 mg$248-In Stock
1 mL x 10 mM (in DMSO)$37-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Batch Information

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Purity:99.70%
Appearance:Viscous
Color:Yellow
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Product Introduction

Bioactivity
Description
Propargylcholine (Propargylcholine (bromide)) is an alkyne-modified choline analog and inhibits choline catabolism at the level of Dgc enzyme-catalyzed dimethylglycine demethylation in Pseudomonas aeruginosa.
SynonymsPropargylcholine (bromide)
Chemical Properties
Molecular Weight208.1
FormulaC7H14BrNO
Cas No.111755-76-1
Smiles[Br-].C[N+](C)(CCO)CC#C
Relative Density.no data available
Storage & Solubility Information
StoragePure form: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMF: 30 mg/mL (144.16 mM), Sonication is recommended.
Ethanol: 30 mg/mL (144.16 mM), Sonication is recommended.
DMSO: 55 mg/mL (264.3 mM), Sonication is recommended.
PBS (pH 7.2): 10 mg/mL (48.05 mM), Sonication is recommended.
Solution Preparation Table
PBS (pH 7.2)/DMF/Ethanol/DMSO
1mg5mg10mg50mg
1 mM4.8054 mL24.0269 mL48.0538 mL240.2691 mL
5 mM0.9611 mL4.8054 mL9.6108 mL48.0538 mL
10 mM0.4805 mL2.4027 mL4.8054 mL24.0269 mL
20 mM0.2403 mL1.2013 mL2.4027 mL12.0135 mL
DMF/Ethanol/DMSO
1mg5mg10mg50mg
50 mM0.0961 mL0.4805 mL0.9611 mL4.8054 mL
100 mM0.0481 mL0.2403 mL0.4805 mL2.4027 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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