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Anti-TYRP1 Polyclonal Antibody
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Catalog No. TMAB-01926
Alias TYRRP, TYRP, TRP1, TRP, OCA3, GP75, CATB, CAS2, b-PROTEIN
Anti-TYRP1 Polyclonal Antibody is a Rabbit antibody targeting TYRP1. Anti-TYRP1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
Anti-TYRP1 Polyclonal Antibody
Anti-TYRP1 Polyclonal Antibody
😃Good
Catalog No. TMAB-01926Alias TYRRP, TYRP, TRP1, TRP, OCA3, GP75, CATB, CAS2, b-PROTEIN
Anti-TYRP1 Polyclonal Antibody is a Rabbit antibody targeting TYRP1. Anti-TYRP1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $222 | 7-10 days | |
| 100 μL | $373 | 7-10 days | |
| 200 μL | $527 | 7-10 days |
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-TYRP1 Polyclonal Antibody is a Rabbit antibody targeting TYRP1. Anti-TYRP1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | TYRRP, TYRP, TRP1, TRP, OCA3, GP75, CATB, CAS2, b-PROTEIN |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Cow,Horse) |
| Verified Activity | 1. Paraformaldehyde-fixed, paraffin embedded (Human skin); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (Tyrosinase-related protein 1) Polyclonal Antibody, Unconjugated (TMAB-01926) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 min and DAB staining. 2. Sample: B16 (Mouse) cell Lysate at 40 μg Primary: Anti-TRP1 (TMAB-01926) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kDa Observed band size: 55 kDa   |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Melanosome membrane; Single-pass type I membrane protein (By similarity). Note=Located to mature stage III and IV melanosomes and apposed endosomal tubular membranes. Transported to pigmented melanosomes by the BLOC-1 complex (By similarity). |
| Tissue Specificity | Pigment cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | TRP1 is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. |
| Immunogen | KLH conjugated synthetic peptide: human TYRP1 |
| Antigen Species | Human |
| Gene Name | TYRP1 |
| Gene ID | |
| Protein Name | 5, 6-dihydroxyindole-2-carboxylic acid oxidase |
| Uniprot ID | |
| Function | Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. |
| Molecular Weight | Theoretical: 58 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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