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Synonyms: TYRRP, TYRP, TRP1, TRP, OCA3, GP75, CATB, CAS2, b-PROTEIN
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $222 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
| Description | Anti-TYRP1 Polyclonal Antibody is a Rabbit antibody targeting TYRP1. Anti-TYRP1 Polyclonal Antibody can be used in IF,IHC-Fr,IHC-P,WB. |
| Synonyms | TYRRP, TYRP, TRP1, TRP, OCA3, GP75, CATB, CAS2, b-PROTEIN |
| Ig Type | IgG |
| Reactivity | Human,Mouse (predicted:Rat,Cow,Horse) |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Subcellular Localization | Melanosome membrane; Single-pass type I membrane protein (By similarity). Note=Located to mature stage III and IV melanosomes and apposed endosomal tubular membranes. Transported to pigmented melanosomes by the BLOC-1 complex (By similarity). |
| Tissue Specificity | Pigment cells. |
| Construction | Polyclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1 mg/mL |
| Research Background | TRP1 is a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. |
| Immunogen | KLH conjugated synthetic peptide: human TYRP1 |
| Antigen Species | Human |
| Gene Name | TYRP1 |
| Gene ID | |
| Protein Name | 5, 6-dihydroxyindole-2-carboxylic acid oxidase |
| Uniprot ID | |
| Function | Oxidation of 5,6-dihydroxyindole-2-carboxylic acid (DHICA) into indole-5,6-quinone-2-carboxylic acid. May regulate or influence the type of melanin synthesized. |
| Molecular Weight | Theoretical: 58 kDa. Actual: 55 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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