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Anti-Phospho-FADD (Ser191) Polyclonal Antibody

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Catalog No. TMAC-01423

Anti-Phospho-FADD (Ser191) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FADD (Ser191). Anti-Phospho-FADD (Ser191) Polyclonal Antibody can be used in WB,IHC.

Anti-Phospho-FADD (Ser191) Polyclonal Antibody

Anti-Phospho-FADD (Ser191) Polyclonal Antibody

😃Good
Catalog No. TMAC-01423
Anti-Phospho-FADD (Ser191) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FADD (Ser191). Anti-Phospho-FADD (Ser191) Polyclonal Antibody can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2167-10 days
100 μL$3177-10 days
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Product Introduction

Bioactivity
Description
Anti-Phospho-FADD (Ser191) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FADD (Ser191). Anti-Phospho-FADD (Ser191) Polyclonal Antibody can be used in WB,IHC.
Ig Type
IgG
Reactivity
Human,Mouse
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-100
Antibody Type
Polyclonal
Host SpeciesRabbit
ConstructionPolyclonal Antibody
PurificationAntibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
AppearanceLiquid
FormulationRabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundThe protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development.
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
Phospho
Antigen Details
Immunogen
Peptide sequence around phosphorylation site of Serine191(N-R-S(p)-G-A) derived from Mouse FADD
Antigen Species
mouse
Uniprot ID
Chemical Properties
Molecular WeightActual: 25 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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