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Anti-Phospho-FADD (Ser191) Polyclonal Antibody
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Catalog No. TMAC-01423
Alias p-FADD (Ser191), p-FADD (S191), FADD (p-Ser191), FADD (p-S191)
Anti-Phospho-FADD (Ser191) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FADD (Ser191). Anti-Phospho-FADD (Ser191) Polyclonal Antibody can be used in IHC,WB.
Anti-Phospho-FADD (Ser191) Polyclonal Antibody
Anti-Phospho-FADD (Ser191) Polyclonal Antibody
😃Good
Catalog No. TMAC-01423Alias p-FADD (Ser191), p-FADD (S191), FADD (p-Ser191), FADD (p-S191)
Anti-Phospho-FADD (Ser191) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FADD (Ser191). Anti-Phospho-FADD (Ser191) Polyclonal Antibody can be used in IHC,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $216 | 7-10 days | 7-10 days | |
| 100 μL | $317 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-FADD (Ser191) Polyclonal Antibody is a Rabbit antibody targeting Phospho-FADD (Ser191). Anti-Phospho-FADD (Ser191) Polyclonal Antibody can be used in IHC,WB. |
| Synonyms | p-FADD (Ser191), p-FADD (S191), FADD (p-Ser191), FADD (p-S191) |
| Ig Type | IgG |
| Reactivity | Human,Mouse |
| Verified Activity | 1. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using FADD (Phospho-Ser191) antibody TMAC-01423 (left) or the same antibody preincubated with blocking peptide (right). 2. Western blot analysis of extracts from Jurkat cells treated with PMA using FADD (Phospho-Ser191) Antibody TMAC-01423. The lane on the right is treated with the antigen-specific peptide.   |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-100 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Appearance | Liquid |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | The protein encoded by this gene is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | Peptide sequence around phosphorylation site of Serine191(N-R-S(p)-G-A) derived from Mouse FADD |
| Antigen Species | mouse |
| Uniprot ID |
| Molecular Weight | Actual: 25 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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