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TargetMol | Compound Library

Neurotransmitter Receptor Compound Library

Catalog No. L2610

A neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is activated by a neurotransmitter. Chemicals on the outside of the cell, such as a neurotransmitter, can bump into its corresponding receptor in the membrane, bind and trigger other events to occur inside the cell. A neurotransmitter receptor is a class of receptors that specifically binds with neurotransmitters as opposed to other molecules. Neurotransmitter (NT) receptors are located on the surface of neuronal and glial cells. There are two major types of neurotransmitter receptors: ionotropic and metabotropic. Ionotropic means that ions can pass through the receptor, whereas metabotropic means that a second messenger inside the cell relays the message (i.e. metabotropic receptors do not have channels). Metabotropic receptors are in fact G protein-coupled receptors. Ionotropic receptors are also called Ligand-gated ion channels and they can be excited by neurotransmitters like glutamate and aspartate. There are several major classes of neurotransmitters: Adrenergic, Dopaminergic, GABAergic, Glutaminergic, Histaminergic, Cholinergic, Opioid, Serotonergic, and Glycinergic. In the brain, most drug targets consist of signaling proteins that go awry in central nervous system diseases, for example with autism in childhood, schizophrenia in adolescence, or Alzheimer's disease in old age. The aim of drug treatment is to correct the inappropriate behavior of these proteins and restore normal brain function. Understanding the effects of neurotransmitters is extremely important in therapeutics. All psychiatric drugs act by affecting neurotransmitters. Understanding their mechanism of action and adverse effects is key to developing new drugs for neurological diseases. The TargetMol neurotransmitter receptor compound library contains 1660 CNS receptor ligands, which is ideal for screening or identifying recombinant orphan G protein-coupled receptors, target validation, secondary screening, validating new assays, and for routine pharmacological applications.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L2610

Neurotransmitter Receptor Compound Library

sizeIn stock

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1660 neurotransmitter receptor compounds, can be used for HTS and HCS screening;
  • Targets include 5-HT receptor, AChR, GABA receptor, dopamine receptor,Opiod receptor, Ionotropic Glutamatergic receptor, Metabotropic Glutamatergic receptor, Purinergic receptor, etc.;
  • Structurally diverse, medicinally active, and cell permeable;
  • Detailed information about compound structure, target, activity, etc.;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

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Targetmol Compound Libraries
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Library Customization | TargetMol Library Composition

5-HT Receptor
AChR
Adrenergic Receptor
Dopamine Receptor
Histamine Receptor
GABA Receptor
Adenosine Receptor
GluR
NMDAR
iGluR
Autophagy
Endogenous Metabolite
Norepinephrine
Apoptosis
Serotonin Transporter
Calcium Channel
Potassium Channel
Sodium Channel
Antibacterial
Cholinesterase (ChE)
PDE
Cytochromes P450
Parasite
Influenza Virus
Sigma receptor
TRP/TRPV Channel
CaMK
HIV Protease
Antibiotic
HCV Protease
HER
NF-κB
Reactive Oxygen Species
Antifungal
HDAC
MAO
ABC Transporter
BACE
COX
Dehydrogenase
DNA/RNA Synthesis
Drug Metabolite
ERK
Ferroptosis
Histone Methyltransferase
Lipoxygenase
Mitophagy
Monoamine Transporter
NO Synthase
Opioid Receptor
P2X Receptor
P-gp
Phospholipase
TNF
AMPK
Beta Amyloid
cAMP
Cannabinoid Receptor
Caspase
Chloride channel
Glucocorticoid Receptor
GPR
Imidazoline Receptor
Monoamine Oxidase
MRP
PI3K
PKA
Prostaglandin Receptor
RAAS
ROS
SARS-CoV
Transferase
VEGFR
Virus Protease
Acyltransferase
Adenylyl Cyclase
Antifection
Anti-infection
Antioxidant
Aurora Kinase
Bcl-2 Family
Beta-Secretase
EGFR
Gamma-secretase
GSK-3
IL Receptor
Immunology/Inflammation related
MEK
Melatonin Receptor
MT Receptor
NOS
PAFR
PARP
Phosphatase
Platelet aggregation
PPAR
STAT
Transaminase
Tyrosinase
ACK1
Adenosine Deaminase
Adiponectin Receptor
Akt
Amino Acids and Derivatives
Aminopeptidase
Androgen Receptor
Angiotensin-converting Enzyme (ACE)
Annexin A
Antifolate
Arrestin
Aryl Hydrocarbon Receptor
ATM/ATR
Bcr-Abl
Bombesin Receptor
Carbonic Anhydrase
CCR
CDK
CRISPR/Cas9
DNA
DNA Methyltransferase
DYRK
Epigenetic Reader Domain
FAK
Fatty Acid Synthase
FGFR
FLT
FXR
Gap Junction Protein
GluCls
Glucosidase
GlyT
GRK
GST
GTPase
HBV
HCN Channel
HIF/HIF Prolyl-Hydroxylase
HMG-CoA Reductase
HSV
Hydroxylase
IAP
Indoleamine 2,3-Dioxygenase (IDO)
Integrin
Interleukin
LDL
Leukotriene Receptor
LTR
Melanin-concentrating Hormone Receptor (MCHR)
Microtubule Associated
Mitochondrial Metabolism
MMP
mTOR
Na+/Ca2+ Exchanger
NADPH
NOD
OCT
p38 MAPK
p53
PAD
PKC
Raf
Reductase
Reverse Transcriptase
RSV
Stearoyl-CoA Desaturase (SCD)
Syk
TGF-beta/Smad
transporter
Trk receptor