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Neurotransmitter Receptor Compound Library

Catalog No. L2610
  Library Compound List   Excel SDF

A neurotransmitter receptor (also known as a neuroreceptor) is a membrane receptor protein that is activated by a neurotransmitter. Chemicals on the outside of the cell, such as a neurotransmitter, can bump into its corresponding receptor in the membrane, bind and trigger other events to occur inside the cell. A neurotransmitter receptor is a class of receptors that specifically binds with neurotransmitters as opposed to other molecules. Neurotransmitter (NT) receptors are located on the surface of neuronal and glial cells.

There are two major types of neurotransmitter receptors: ionotropic and metabotropic. Ionotropic means that ions can pass through the receptor, whereas metabotropic means that a second messenger inside the cell relays the message (i.e. metabotropic receptors do not have channels). Metabotropic receptors are in fact G protein-coupled receptors. Ionotropic receptors are also called Ligand-gated ion channels and they can be excited by neurotransmitters like glutamate and aspartate. There are several major classes of neurotransmitters: Adrenergic, Dopaminergic, GABAergic, Glutaminergic, Histaminergic, Cholinergic, Opioid, Serotonergic, and Glycinergic.

In the brain, most drug targets consist of signaling proteins that go awry in central nervous system diseases, for example with autism in childhood, schizophrenia in adolescence, or Alzheimer's disease in old age. The aim of drug treatment is to correct the inappropriate behavior of these proteins and restore normal brain function. Understanding the effects of neurotransmitters is extremely important in therapeutics. All psychiatric drugs act by affecting neurotransmitters. Understanding their mechanism of action and adverse effects is key to developing new drugs for neurological diseases.

The TargetMol neurotransmitter receptor compound library contains 1513 CNS receptor ligands, which is ideal for screening or identifying recombinant orphan G protein-coupled receptors, target validation, secondary screening, validating new assays, and for routine pharmacological applications.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Compound Libraries | TargetMol
Pack Size
1 mg
30 μL * 10 mM (in DMSO)
50 μL * 10 mM (in DMSO)
100 μL * 10 mM (in DMSO)
250 μL * 10 mM (in DMSO)
If the above compound libraries do not match your needs,
please contact our compound library specialist for a customized compound library at inquiry@targetmol.com
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Product Description

  • A unique collection of 1513 neurotransmitter receptor compounds, can be used for HTS and HCS screening;
  • Targets include 5-HT receptor, AChR, GABA receptor, dopamine receptor,Opiod receptor, Ionotropic Glutamatergic receptor, Metabotropic Glutamatergic receptor, Purinergic receptor, etc.;
  • Structurally diverse, medicinally active, and cell permeable;
  • Detailed information about compound structure, target, activity, etc.;
  • NMR and HPLC/LCMS validated to ensure high purity and quality.

Library Customization

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Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice
Request Library Compound List (L2610)

Publications Cited TargetMol Libraries

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Library Composition

5-HT Receptor (347)
AChR (277)
Dopamine Receptor (219)
Adrenergic Receptor (212)
Histamine Receptor (152)
GABA Receptor (141)
GluR (91)
Opioid Receptor (72)
Adenosine Receptor (72)
AChE (71)
iGluR (68)
NMDAR (63)
Autophagy (56)
Endogenous Metabolite (54)
Apoptosis (40)
Norepinephrine (31)
Serotonin Transporter (28)
Antibacterial (27)
Calcium Channel (24)
Potassium Channel (23)
Parasite (19)
Sodium Channel (18)
Neuropeptide Y Receptor (17)
Endothelin Receptor (17)
P450 (15)
PDE (14)
Influenza Virus (11)
NF-κB (9)
Antibiotic (7)
cholecystokinin (7)
Antifungal (7)
HIV Protease (7)
CaMK (7)
HDAC (6)
Phospholipase (6)
Reactive Oxygen Species (6)
COX (6)
TRP/TRPV Channel (5)
P-gp (5)
TNF (5)
Mitophagy (5)
HCV Protease (5)
Monoamine Transporter (4)
Adenosine deaminase (4)
NO Synthase (4)
Histone Methyltransferase (4)
DNA/RNA Synthesis (4)
Ferroptosis (4)
MAO (4)
ERK (4)
Dehydrogenase (4)
Beta Amyloid (4)
Virus Protease (4)
Sigma receptor (4)
HSV (3)
Prostaglandin Receptor (3)
Monoamine Oxidase (3)
Chloride channel (3)
P2X Receptor (3)
Transferase (3)
Drug Metabolite (3)
Cannabinoid Receptor (3)
BACE (3)
RAAS (3)
Beta-Secretase (3)
Tyrosinase (3)
Glucocorticoid Receptor (3)
ABC (3)
GPR (3)
AMPK (3)
VEGFR (3)
PI3K (3)
Caspase (3)
RSV (2)
Aurora Kinase (2)
mTOR (2)
cAMP (2)
IL Receptor (2)
Lipoxygenase (2)
HER (2)
SARS-CoV (2)
BCL (2)
PPAR (2)
Adenylyl cyclase (2)
NOS (2)
Transaminase (2)
Imidazoline Receptor (2)
Antioxidant (2)
DYRK (2)
Phosphatase (2)
GSK-3 (2)
Melatonin Receptor (2)
ROS (2)
PKA (2)
HBV (2)
MRP (2)
PARP (2)
MEK (2)
Anti-infection (2)
Gamma-secretase (2)
PAFR (2)
GST (1)
Hydroxylase (1)
GluCls (1)
FGFR (1)
p53 (1)
FAK (1)
HIF/HIF Prolyl-Hydroxylase (1)
Microtubule Associated (1)
DNA Methyltransferase (1)
Reverse Transcriptase (1)
Gap Junction Protein (1)
STAT (1)
Nrf2 (1)
FLT (1)
Syk (1)
HMG-CoA Reductase (1)
NOD (1)
CRISPR/Cas9 (1)
Platelet aggregation (1)
Melanin-concentrating Hormone Receptor (MCHR) (1)
Aminopeptidase (1)
OCT (1)
Adiponectin receptor (1)
Annexin A (1)
Immunology/Inflammation related (1)
IAP (1)
Aryl Hydrocarbon Receptor (1)
PKC (1)
Leukotriene Receptor (1)
FXR (1)
Antifolate (1)
Progesterone Receptor (1)
LDL (1)
GTPase (1)
NADPH (1)
Arrestin (1)
Na+/Ca2+ Exchanger (1)
Estrogen/progestogen Receptor (1)
p38 MAPK (1)
Amino Acids and Derivatives (1)
Integrin (1)
Carbonic Anhydrase (1)
CAT (1)
Bcr-Abl (1)
GRK (1)
Trk receptor (1)
Epigenetic Reader Domain (1)
Acyltransferase (1)
MAPK (1)
Akt (1)
EGFR (1)
TGF-beta/Smad (1)
Interleukin (1)
Androgen Receptor (1)
Indoleamine 2,3-Dioxygenase (IDO) (1)
DNA (1)
ACK (1)
Raf (1)
PAD (1)
MMP (1)
CCR (1)
Stearoyl-CoA Desaturase (SCD) (1)
Bombesin Receptor (1)
Antifection (1)
Mitochondrial Metabolism (1)
Glucosidase (1)
GlyT (1)
MT Receptor (1)
Fatty Acid Synthase (1)

Library Information Sample

Empty 1000025-07-9 1000413-72-8 229005-80-5 1000787-75-6 946387-07-1 1000998-59-3 1175526-27-8 1001288-58-9 1001350-96-4 1001404-83-6 Empty
Vadadustat TAK875 TAK-779 Tegobuvir RN-1734 BMS-687453 AM211 FT011 BMS754807 AAI101
Empty 1001625-82-6 1001645-58-4 1001753-24-7 1001908-89-9 1002304-34-8 1002-84-2 100291-86-9 100299-08-9 10030-52-1 10040-45-6 Empty
RPW-24 SRT1720 hydrochloride INH6 SRT 2183 AMG208 Pentadecanoic acid Apiopaeonoside Pemirolast potassium L-Anserine nitrate salt Sodium Picosulfate
Empty 100427-26-7 1004316-88-4 10045-45-1 100462-37-1 1004990-28-6 100-51-6 1005-24-9 1005264-47-0 1005334-57-5 1005342-46-0 Empty
Lercanidipine Cobicistat 1-Ethyl-2-benzimidazolinone ROSIRIDIN PF-AKT400 Benzyl alcohol 1-Methylnicotinamide chloride MX69 CVT-10216 LCL161
Empty 1005491-05-3 100-55-0 1005504-62-0 1005883-72-6 100643-71-8 1007207-67-1 10075-50-0 1007647-73-5 100784-20-1 10083-24-6 Empty
Tirasemtiv Roniacol Rg3039 Z433927330 Desloratadine CH5132799 5-Bromoindole Smurf1-IN-A01 Halosulfuron-methyl Piceatannol
Empty 100872-83-1 100874-08-6 1009119-64-5 1009119-65-6 100929-71-3 1009298-09-2 1009298-59-2 100929-99-5 1009734-33-1 10097-84-4 Empty
ML346 SB 4 Daclatasvir Daclatasvir dihydrochloride NADPH (tetracyclohexanamine) AZD8055 Vistusertib PAβN dihydrochloride HZ1157 Rotundine
Empty 1009816-48-1 1009817-63-3 1009820-21-6 100986-85-4 101001-34-7 1010411-21-8 1010-60-2 1011244-68-0 1011301-27-1 1011529-10-4 Empty
Thiamet G B-AP15 Silmitasertib Levofloxacin Pamicogrel GSK369796 Dihydrochloride 2-Chloronaphthoquinone TFAP Tenovin3 Azvudine
Empty 101152-94-7 101155-02-6 1011557-82-6 1011-74-1 101-20-2 1012054-59-9 101-21-3 101-26-8 101303-98-4 1013101-36-4 Empty
Milnacipran hydrochloride BW-A78U Tenovin-6 DL-Normetanephrine hydrochloride Triclocarban CUDC101 Chlorpropham Mestinon Zacopride hydrochloride PF04691502
Empty 101-31-5 1013-69-0 1013750-77-0 1013753-99-5 10138-52-0 1013920-15-4 1013937-63-7 1014691-61-2 101477-54-7 101494-95-5 Empty
L-Hyoscyamine Noreugenin ML-030 BC-1382 Gadolinium chloride Vorolanib VTP-27999 TFA GSK0660 Lomerizine hydrochloride 8-CHLOROQUINAZOLIN-4(1H)-ONE
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