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Anti-DUSP1 Antibody (4S873) (Synonyms: VH1, VH 1, Serine/threonine specific protein phosphatase, Ptpn16, PTP...)
Catalog No. TMAC-01190 Copy Product Info
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Anti-DUSP1 Antibody (4S873) is a Rabbit antibody targeting DUSP1. Anti-DUSP1 Antibody (4S873) can be used in FCM,ICC/IF,IHC,IP,WB.
Anti-DUSP1 Antibody (4S873)
Copy Product Info🥰Excellent
Catalog No. TMAC-01190
Synonyms VH1, VH 1, Serine/threonine specific protein phosphatase, Ptpn16, PTPN10, PTPN 10, Protein tyrosine phosphatase CL100, Mkp1, MKP 1, Mitogen activated protein kinase phosphatase 1, MAP kinase phosphatase 1, HVH1, HVH 1, EC 3.1.3.48, EC 3.1.3.16, DUSP-1, DUSP1, Dual specificity protein phosphatase hVH1, Dual specificity protein phosphatase 1, Dual Specificity Phosphatase 1, CL100, CL 100, 3ch134
Anti-DUSP1 Antibody (4S873) is a Rabbit antibody targeting DUSP1. Anti-DUSP1 Antibody (4S873) can be used in FCM,ICC/IF,IHC,IP,WB.
Anti-DUSP1 Antibody
(4S873)
(4S873)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $496 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-DUSP1 Antibody (4S873) is a Rabbit antibody targeting DUSP1. Anti-DUSP1 Antibody (4S873) can be used in FCM,ICC/IF,IHC,IP,WB. |
| Synonyms | VH1, VH 1, Serine/threonine specific protein phosphatase, Ptpn16, PTPN10, PTPN 10, Protein tyrosine phosphatase CL100, Mkp1, MKP 1, Mitogen activated protein kinase phosphatase 1, MAP kinase phosphatase 1, HVH1, HVH 1, EC 3.1.3.48, EC 3.1.3.16, DUSP-1, DUSP1, Dual specificity protein phosphatase hVH1, Dual specificity protein phosphatase 1, Dual Specificity Phosphatase 1, CL100, CL 100, 3ch134 |
| Ig Type | IgG |
| Clone | 4S873 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of DUSP1 on mouse spleen lysates using anti-DUSP1 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human lung cancer tissue using anti-DUSP1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded mouse lung tissue using anti-DUSP1 antibody. Counter stained with hematoxylin. 4. Flow cytometric analysis of HepG2 cells with DUSP1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.     |
| Application | |
| Recommended Dose | WB: 1:1000<:br>IHC: 1:50-200<:br>FCM: 1:50-100<:br>ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | A key element in the pathway involved in the transduction of signals from activated protein-tyrosine kinase transmembrane receptors has been identified as the family of mitogen-activated protein kinases (MAP kinases). The most well known of these Ser/Thr kinases are ERK 1 and ERK 2. Mitogenic stimulation of cells triggers the activation of MAP kinases through phosphorylation of both tyrosyl (Y185) and threonyl (T183) residues. Phosphorylation of the T183 and Y185 ERK regulatory site is mediated by MAP kinase (MEK), which in turn is regulated by the proto-oncogene product Raf. Two highly related phosphatases, designated MKP-1 and MKP-2, exhibit 59% sequence identity at the amino acid level and oppose the action of MEK by downregulating the kinase activity of ERK 1 and ERK 2. MAP kinase phosphatase-1 and -2 proteins function by dephosphorylating ERK 1 and ERK 2 at their T-E-Y regulatory motif. An additional phosphatase encoded by the DUSP2 gene, designated PAC-1, also functions to downregulate ERK 1 and ERK 2 kinase activity. PAC-1 is a nuclear protein whose expression is strongly induced in response to mitogen. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 40 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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