Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will result in gastric cancer and prostate cancer.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 μg | 5 days | $ 184.00 | |
50 μg | 5 days | $ 545.00 | |
500 μg | 5 days | $ 1,900.00 | |
1 mg | 5 days | $ 2,970.00 |
Description | Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will result in gastric cancer and prostate cancer. |
Species | Human |
Expression System | E. coli |
Tag | None |
Accession Number | Q99612-3 |
Synonyms | CPBP, GC-Rich Sites-Binding Factor GBF, Suppressor of Tumorigenicity 12 Protein, ST12, KLF6, Transcription Factor Zf9, Krueppel-Like Factor 6, BCD1, B-Cell-Derived Protein 1, COPEB, Core Promoter Element-Binding Protein, Proto-Oncogene BCD1 |
Amino Acid | Met1-Ser109 |
Construction | Recombinant Human Krueppel-like Factor 6 is produced by our E.coli expression system and the target gene encoding Met1-Ser109 is expressed. |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
Molecular Weight | 13-19 KDa, reducing conditions |
Endotoxin | Less than 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
Shipping |
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature listed below. |
Research Background | Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will result in gastric cancer and prostate cancer. |
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Please read the User Guide of Recombinant Proteins for more specific information.
KLF6 Protein, Human, Recombinant CPBP KLF 6 GC-Rich Sites-Binding Factor GBF Suppressor of Tumorigenicity 12 Protein ST12 KLF6 BCD 1 Transcription Factor Zf9 BCD-1 Krueppel-Like Factor 6 KLF-6 ST-12 BCD1 B-Cell-Derived Protein 1 COPEB Core Promoter Element-Binding Protein Proto-Oncogene BCD1 ST 12 recombinant recombinant-proteins proteins protein