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Anti-Phospho-Presenilin 1 (Ser357) Polyclonal Antibody
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Catalog No. TMAC-03418
Alias Presenilin 1 (p-Ser357), Presenilin 1 (p-S357), p-Presenilin 1 (Ser357), p-Presenilin 1 (S357)
Anti-Phospho-Presenilin 1 (Ser357) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Presenilin 1 (Ser357). Anti-Phospho-Presenilin 1 (Ser357) Polyclonal Antibody can be used in ELISA,IF,IHC-P,WB.
Anti-Phospho-Presenilin 1 (Ser357) Polyclonal Antibody
Anti-Phospho-Presenilin 1 (Ser357) Polyclonal Antibody
😃Good
Catalog No. TMAC-03418Alias Presenilin 1 (p-Ser357), Presenilin 1 (p-S357), p-Presenilin 1 (Ser357), p-Presenilin 1 (S357)
Anti-Phospho-Presenilin 1 (Ser357) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Presenilin 1 (Ser357). Anti-Phospho-Presenilin 1 (Ser357) Polyclonal Antibody can be used in ELISA,IF,IHC-P,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $217 | 7-10 days | 7-10 days | |
| 100 μL | $317 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-Phospho-Presenilin 1 (Ser357) Polyclonal Antibody is a Rabbit antibody targeting Phospho-Presenilin 1 (Ser357). Anti-Phospho-Presenilin 1 (Ser357) Polyclonal Antibody can be used in ELISA,IF,IHC-P,WB. |
| Synonyms | Presenilin 1 (p-Ser357), Presenilin 1 (p-S357), p-Presenilin 1 (Ser357), p-Presenilin 1 (S357) |
| Ig Type | IgG |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC-P: 1:100-300; ELISA: 1:5000 |
| Antibody Type | Polyclonal |
| Host Species | Rabbit |
| Construction | Polyclonal Antibody |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Appearance | Liquid |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Research Background | presenilin 1(PSEN1) Homo sapiens Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Several alternatively spliced transcript variants encoding different isoforms have been identified for this gene, the full-length nature of only some have been determined. [provided by RefSeq, Aug 2008], |
| Conjucates | Unconjugated |
| Others Formats | Phospho |
| Immunogen | A synthesized phosphopeptide: human PSEN1 around the phosphorylation site of Ser357. AA range:323-372 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Actual: 43 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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